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Bipolar Disorder

Researchers from McLean Hospital report details of new studies and findings in the area of bipolar disorder

Published in Hospital Law Weekly, March 4th, 2010

"There are substantial abnormalities in the number, density, and size of cortical neurons and glial cells in bipolar disorder and schizophrenia. Because molecule-microenvironment interactions modulate metabolite signals characteristics, these cellular abnormalities may impact transverse (T-2) relaxation times," researchers in the United States report.

"We measured T-2 relaxation times for three intracellular metabolites (N-acetylaspartate + N-acetylaspartylglutamate, creatine + phosphocreatine, and choline-containing compounds) in the anterior cingulate cortex and parieto-occipital cortex from 20 healthy subjects, 15 patients with bipolar disorder, and 15 patients with...

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