University of Utah

Distinct immunohistochemical features of pediatric BL and DLBCL identified

Published in Hospital and Nursing Home Week, April 15th, 2004

Several diagnostically valuable immunohistochemical features of pediatric Burkitt lymphoma (BL) and diffuse large B-cell lymphoma (DLBCL) have been identified.

BL and DLBCL "account for nearly all pediatric nonlymphoblastic B-cell lymphomas," scientists in the United States explained. "Because clinical behavior, prognosis, and response to therapy might differ, diagnostic accuracy is important."

"Morphologic examination often is sufficient, but occasionally, diagnostic ancillary studies are required," noted M. Frost and colleagues at the University of Utah. "In adults, immunophenotyping is useful; however, pediatric data are limited."

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Source: Hospital and Nursing Home Week (2004-04-15)

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