Karolinska Institute
Functional entities augment and optimize plasmid based therapies
Published in Hospital and Nursing Home Week, May 6th, 2004
According to recent research published in the Journal of Gene Medicine, "non-viral gene therapy constitutes an alternative to the more common use of viral-mediated gene transfer. Most gene transfer methods using naked DNA are based upon non-sequence-specific interactions between the nucleic acid and cationic lipids (lipoplex) or polymers (polyplex). We have developed a technology in which functional entities hybridize in a sequence-specific manner to the nucleic acid (bioplex).
"This technology is still in its infancy, but has the potential to become a useful tool, since it...
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