Bellvitge University Hospital
Neuropathology of encephalitis after A-beta immunization described
Published in Hospital and Nursing Home Week, May 27th, 2004
"Beta-amyloid deposition resembling plaques in Alzheimer disease (AD) results in a decrease of amyloid burden when compared with non-treated transgenic animals. Immunization with amyloid-beta peptide has been initiated in a randomized pilot study in AD. Yet a minority of patients developed a neurological complication consistent with meningoencephalitis and one patient died; the trial has been stopped," investigators in Spain report.
"Neuropathological examination in that...
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