Emory University
Proteomic analysis of rat brain postsynaptic density fractions reported
Published in Hospital and Nursing Home Week, August 5th, 2004
According to published research from the United States, "The postsynaptic density (PSD) of central excitatory synapses plays a key role in postsynaptic signal transduction and contains a high concentration of glutamate receptors and associated scaffold and signaling proteins. We report here a comprehensive analysis of purified PSD fractions by liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS). We identified 374 different proteins that copurified with the PSD structure and discovered 13 phosphorylated sites from eight...
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