Published in Hospital and Nursing Home Week, March 10th, 2005
Previous studies "conducted in MCF7-ptsp53 cells have demonstrated that overexpression of the wild-type (wt) p53 at permissive temperature 32 degrees C leads to growth arrest at the G2 /M phase of the cell cycle," scientists in California explained.
"To identify novel p53-regulated genes that are responsible for the p53-induced G2 /M arrest," C. Li and coauthors at the VA Palo Alto Health Care System performed a series of "cDNA microarray analyses."
The mRNA level of PRC1 "was...
Want to see the full article?
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Hospital and Nursing Home Week
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.