Medical University of South Carolina
Studies add new findings to cardiology body of knowledge
Published in Hospital and Nursing Home Week, April 20th, 2006
Study 1: Angiogenesis prevailed despite matrix enzyme deletion following myocardial infarction (MI).
According to recent research from the United States, "matrix metalloproteinases (MMPs) are postulated to be necessary during wound healing. MMP-9 deletion alters remodeling post-MI, but whether and to what degree MMP-9 affects neovascularization post-MI is unknown."
"Neovascularization was evaluated in wild-type (WT; n=63) and MMP-9 null (n=55) mice at 7-days post-MI. Despite similar infarct sizes, MMP-9 deletion improved left ventricular function as...
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