West Virginia University, U.S.
Sperm DNA vaccine has contraceptive effects in female mice
Published in Hospital and Nursing Home Week, August 10th, 2006
According to researchers in the United States, "Our laboratory has identified a sperm-specific dodecamer peptide sequence, designated as YLP12, vaccination with which causes a long-term reversible immunocontraceptive effect in female mice. In the present study, the effects of YLP12 DNA vaccine were examined."
Rajesh K. Naz at West Virginia University explained, "YLP12 36 bp cDNA was cloned into pVAX1 vector to prepare the DNA vaccine. Two additional vaccine constructs were made by in frame cloning of one and two CpG repeats in the YLP12-cDNA vaccine. Five groups of female mice...
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