Alzheimer Disease

New data from University of Tasmania, Menzies Research Institute illuminate research in Alzheimer disease

Published in Hospital and Nursing Home Week, May 15th, 2008

Investigators publish new data in the report 'Network dysfunction in Alzheimer's disease: does synaptic scaling drive disease progression.' "Accumulation of beta-amyloid protein (Abeta) in the brain is a key feature of Alzheimer's disease (AD). The build-up of aggregated forms of Abeta leads to synaptic loss and to cognitive dysfunction," researchers in Hobart, Australia report.

"Although the pathways controlling production and aggregation of Abeta are well studied, the mechanisms that drive the spread of neurodegeneration in the brain are unclear. Here, the idea is presented that AD progresses as a consequence of synaptic scaling, a type of neuronal plasticity that...

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Source: Hospital and Nursing Home Week (2008-05-15)

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