Published in Hospital and Nursing Home Week, August 7th, 2008
Two Phase 1 studies evaluated (i) plasma concentrations from single rising doses in 30 young and 12 elderly volunteers and (ii) 14-day chronic dosing in a second set of 12 young and 12 elderly volunteers. No significant adverse events were registered in single doses from 5 to 405 mg for young subjects, in single doses from 45 to 135 mg for elderly...
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