Emphysema

New monoclonal antibodies research has been reported by scientists at Ohio State University

Published in Hospital and Nursing Home Week, August 28th, 2008

"Sezary Syndrome (SS) is an aggressive T-cell malignancy often presenting in advanced age and associated with poor prognosis. There is no standard therapy and because of co-morbidities, elderly patients are particularly challenging to treat," investigators in the United States report.

"Alemtuzumab is an anti-CD52 monoclonal antibody that has activity in SS but is profoundly immunosuppressive, leading to great hesitation about its use in older patients. We treated five octogenarian patients with SS with subcutaneous (SQ) alemtuzumab, at relapse or as initial therapy, for 5-9 weeks. With the exception of transient grade 1-2 hematological toxicity and asymptomatic...

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Source: Hospital and Nursing Home Week (2008-08-28)

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