Published in Immunotherapy Weekly, June 22nd, 1998
MIP-1(alpha) is not required to control virus growth in the cornea, however, indicated Terrence M. Tumpey, University of South Alabama, and colleagues ("Absence of Macrophage Inflammatory Protein-1(alpha) Prevents the Development of Blinding Herpes Stromal Keratitis," Journal of Virology, 1998;72:3705-3710).
Herpes simplex virus type 1 (HSV-1) infection of the murine cornea triggers an intense inflammatory response (herpes stromal keratitis [HSK]) that persists and can lead to blindness. HSK is characterized by...
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