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Cancer Immunotherapy

Two-Stage Approach Achieves 20-Fold Uptake Of Chemotherapeutic

Published in Immunotherapy Weekly, May 16th, 2001

Immunomedics, Inc. (IMMU) presented results May 2, 2001, on a new method for improved targeting of drugs and isotopes to cancers.

Dr. David M. Goldenberg, Immunomedics, described progress being made in collaboration with its affiliated company, IBC Pharmaceuticals, LLC (IBC), with the next-generation method of pretargeting involving bispecific, or two-armed, antibodies. IBC has broad patent coverage for the pretargeting methodology, referred to as Affinity Enhancement System, or AES, in the scientific literature.

Goldenberg explained that "conventional methods have involved directly attaching therapeutic drugs or isotopes to antibodies, and these...

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