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Type 1 Diabetes

Finding Of Key Blood Sugar Controller Could Yield New Diabetes Drugs

Published in Immunotherapy Weekly, October 3rd, 2001

Dana-Farber Cancer Institute researchers have discovered the long-sought molecular "switch" that regulates the liver's production of glucose, the sugar that fuels the brain but which builds up dangerously in the bloodstream of diabetics because this switch doesn't turn off.

The researchers say it may be possible to design new drug treatments for diabetes as a result of the work.

The finding describes for the first time the exact on-off mechanism that in normal people helps the body maintain a precise level of glucose in the blood. It's a delicate and crucial balance. The brain depends on a constant supply of glucose no matter whether the person is...

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