Immunotherapy Weekly

Immune Evasion - MprF-mediated lysinylation protects S. aureus from neutrophils

Immunology - Bone cement particles can induce raised TNF-alpha production in vitro

Inflammatory Bowel Disease - Butyrate modulates intestinal epithelial cell-mediated neutrophil migration

Inflammatory Bowel Disease - Metallothionein expression is lower in ulcerative colitis and Crohn disease

Inflammatory Response - Compstatin could be used in developing species-specific complement inhibitors

Influenza - Maternal illness causes behavioral and drug-related changes in offspring

Intestinal Inflammation - The study of heat shock proteins can lead to better cytoprotective therapy

Kidney Transplant - A new risk factor to consider is cytomegalovirus-produced cellulitis

Kidney Transplant - Cells in urine distinguish rejection and cyclosporin/tacrolimus nephropathy

Kidney Transplantation - Bone marrow cells can induce anti-B-cell T-cell activity

Kidney Transplantation - Lp(a), LDL deposition in acute kidney rejection analogous to atherosclerosis

Leukocyte Vasculitis - A chronic Epstein-Barr virus infection can cause neuropathy and skin erythema

Listeria Infection - Immunomagnetic separation can be used to detect pathogenic Listeria spp.

Lung Transplantation - EBV serology has limited value in posttransplant lymphoproliferative disease

Lupus Erythematosus - Glomerulonephritis may result from slowed nucleosome waste disposal

Mergers and Acquisitions - Immunotherapeutics companies announce plans to merge

Mesothelioma Risk - Lung disease is caused by asbestos and non-asbestos mineral deposit use

Metastatic Calcification - Sudden death in a kidney recipient after 14 years implicates calcification

Monocytic Ehrlichiosis - Heterogeneity in E. chaffeensis genome could be result of selection process

Multiple Sclerosis - Long-term effect of interferons still in doubt

Multiple Sclerosis Therapy - T cell vaccine shows promise in preliminary trial

Myelination - Adhesion molecules in the immunoglobulin superfamily play a role

Nail Reconstruction - Non-nail-matrical epidermal grafts can treat deepithelized nail injuries

Neurologic Tumors - Pediatric cases were found to test negative for most common autoantibodies

Neutrophil Exocytosis - VAMP-2 mediates exocytosis of specific and tertiary granules

Non-Hodgkin Lymphoma - Radioimmunotherapy for non-Hodgkin lymphoma reviewed

Novel Human pp-GaINAc-T Clone - pp-GalNAc-T13 responsible specifically for the Tn antigen epitope in neurons

Oncogenicity - Critical alteration leading to differences may be INF 7-related effect

Osteoarthritis - UNC researchers awarded $4 million to conduct clinical research on arthritis

Ovarian Cancer - Tumor lymphocytic infiltrate show depleted CD8+, CD56+ immunophenotypic profile

Papillomavirus - HPV evades innate immunity by blocking interferon and immune activation

Pneumonia, Rhinitis, and Asthma - Krumdieck technique allows study of mechanisms of bacterial and viral infections

Primitive Immunology - Evolutionary conservation leads to hypothesis on Toll-like receptor function

Primitive Immunology - Plant resistance genes are similar to animal innate immunity receptors

Pseudomonas Aeruginosa - Molecular is more accurate than phenotypic typing, especially in cystic fibrosis

Renal Failure - Backache and renal failure can be due to septicemia; cured by antibiotics

Renal Transplantation - Daclizumab dosing regimen useful for effective maintenance immunosuppression

Renal Transplantation - Long-term use of MMF helpful in reduction of late rejection

Respiratory Syncytial Virus - Replication is inhibited inversely to NO production of target cells

Respiratory Virus Infections - Lymphocytes and mast cells accumulate during symptomatic natural colds

Rheumatoid Arthritis - Women with RA have marked risk for heart attack

Saccharomyces Cerevisiae - Rim101p governs cell differentiation by directly repressing NRG1 and SMP1

Sepsis - Inhibiting multiple cytokines, augmenting immune response key at different times

Staphylococcus Aureus - SarA mutation reduces septic arthritis and osteomyelitis pathogenesis

Streptococcus Pneumoniae - Invasiveness is caused by low antibody titer to capsular polysaccaride

Systemic Lupus Erythematosus - Immunoglobulins encoded by V-H gene V4-34 show selective rise in SLE

Traditional Herbal Medicine - LPS-induced death was avoided using Physalis angulata L seco-steroids

Transplant Medicine - HLA-G may be factor in graft rejection

Type 1 Diabetes - Proposed treatment for diabetes could have devastating side effects

Tyrosine-Phosphorylated Protein - pp100 has role in T cell activation augmented by TCR/CD3-mediated main signal

Virology - Expanded clinical data on Ampligen in HIV disease to be presented

Wound Dynamics - Vimentin is secreted by activated macrophages; TNF-alpha upregulates it

sarA Homolog - sarU, repressed by SarT, regulates virulence genes in S. aureus