HSV-2 Infection

Peptide 55 had highest efficiency, accuracy in anti-HSV-2 antibody detection

Published in Immunotherapy Weekly, March 12th, 2003

"Assays for serological diagnosis of HSV-2 infection in clinical settings have been generally available only recently. We wanted to investigate and compare the diagnostic utility of three different ELISAs for detection of anti-HSV-2 IgG antibodies, using intact glycoprotein G or an oligopeptide from a portion of the protein as antigens.

"HSV-1 negative/HSV-2 negative sera (n=32), HSV-1 positive/HSV-2 negative sera (n=30) and sera from HSV-2 culture positive individuals (n=36), collected at least 6 months after culture verified HSV-2 genital infection were examined," researchers in Norway report.

"Cut-off values were determined according to the...

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Source: Immunotherapy Weekly (2003-03-12)

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