Immunotherapy Weekly

Immunotoxicology - Whole-blood cytokine release models evaluated as test strategy

Implants - SPARC is an important modulator of the encapsulation of implanted biomaterials

Infectious Disease Model - Zebrafish can be used to study innate immunity and immune response to infections

Inflammatory Bowel Disease - Anti-TNF therapy is now available for clinical use in treating Crohn disease

Influenza - Neuraminidase inhibitors work as well in outpatient practice as in trials

Limb Transplantation - Hand transplant recipients continue to gain new function

Lung Disease - Cell model system can be used for study of effects of ozone on phagocytic cells

Lung Fibrosis - There are some fibrogenic cytokines and growth factors that may be responsible

Lymphocyte Subsets - During the first year of life there are normal variations in cell numbers

Malignant Mesothelioma - TGF-beta inhibits interferon-gamma synthesis by anti-PPD CD4(+) T-cell clone

Mental Health - The inflammation markers haptoglobin and C-reactive protein lower cognition

Metastatic Cytology - Nasopharyngeal origin is distinguishable from other lymph node cancers

Microscopic Polyangiitis - Pulmonary interstitial fibrosis may occur in some cases even before disease

Molecular Cloning - cDNA clone M17 shares sequence similarity with IL-6 subfamily cytokines

Mycotoxicosis - Little evidence of serious illness due to Stachybotrys chartarum

Neuroimmune Response - IL-1beta affects excitability of paraventricular nucleus parvocellular neurons

Nocardia Infections - Clinical success was obtained with linezolid singly or in combination

Ovarian Follicles - Cell death is avoided partially by expression of antiapoptotic proteins

Pediatric Arteritis - Large vessel arteritis may be associated with active human herpesvirus 6

Pemphigus Foliaceus - Subclass switching has role in the pathogenesis of endemic disease

Penicillin Allergy - Anaphylactic shock occurs after a traditional Russian "beauty" treatment

Phenotype Prediction - Scianna is last protein-based blood group system whose molecular basis discerned

Primary Biliary Cirrhosis - Idiotype-antiidiotype-based ELISA of UDCA 7-NAG has subfemtomole sensitivity

Psoriasis Vulgaris - Opioid receptor antagonists have high antipruritic potency in skin diseases

Pulmonary Sarcoidosis - Genomic instability found in mismatch repair genes, and CD48 and IRF4 loci

Respiratory Disease - Asthma patients have an increased prevalence of irritable bowel syndrome

Respiratory Syncytial Virus - RSV and virus-induced inflammation are modified by contaminants of indoor air

Respiratory Syndrome Virus - Increase in IFN-gamma positive cells correlates well with lung lesion severity

Rheumatoid Arthritis - Autoantibodies against cytoskeletal proteins actin and myosin are very high

Rheumatoid Arthritis - BV14, and not BV6, T-cell clonotype is associated with severe disease

Rheumatoid Arthritis - Enbrel 4-year data supports inhibition of bone, joint damage

Rheumatoid Arthritis - Novel autoantibodies that can be used in diagnosis are being discovered

Skin Disease - Human beta defensin 2 has role after bacterial infection in host defense

Spongiform Encephalopathies - Immunocytochemistry is useful tool for diagnosis in liquid-state samples

Statin Expression - Cortistatin has role as endogenous ligand of sst(2) receptor in immune system

Synchronous Cancer - Splenic marginal zone lymphoma found paired with granular T-cell proliferation

Systemic Lupus Erythematosus - Anti-DNA autoantibody-DNA interactions can be modulated by an RNA aptamer

Systemic Lupus Erythematosus - Neuropsychiatric symptoms are varied and tend to occur at disease onset

T-Cell Differentiation - DeltaRec2 rearrangements are transient steps in recombinatorial process of TCRAD

Testis Development/Spermatogenesis - ERalpha and beta in testis suggests that estrogens directly affect germ cells

Therapeutic Recombinant Protein - BL21 strain is useful for reducing risk linked with endotoxin contamination

Therapy - Dendritic cells engineered to express IL-4 accelerate graft rejection

Thrombocythemia - Bone marrow histology differentiates essential from myelofibrotic forms

Toxicology - Approaches to sensitization testing of chemicals are described

Transplant Medicine - Passive transfer of nut allergy occurs after a liver transplantation

Trichomonas Vaginalis - The urine-based PCR-ELISA may be useful for detection of trichomoniasis in men

Trophoblast Implantation - Adhesion, invasiveness, and differentiation involve complex mechanisms

Tuberous Sclerosis - Unexpected death is the most serious of many complications of tuberous sclerosis

Type 1 Diabetes Risk Factor - Vitamin D deficiency increases risk of autoimmune diabetes

Vaccine Safety - Occult orbital neuroblastoma detected after antitumor vaccine