Lymphocyte Apoptosis
Interferon regulatory factor 4 regulates by modulating Fas-mediated apoptosis
Published in Immunotherapy Weekly, April 16th, 2003
According to recent research from the United States, "To ensure that homeostasis of the immune system is maintained, the sensitivity of lymphocytes to Fas-mediated apoptosis is differentially regulated during their activation.
"The molecular mechanisms that link the activation program of lymphocytes to changes in sensitivity to Fas-mediated apoptosis have, however, not been fully characterized. In these studies, we have investigated whether Fas-mediated apoptosis can be regulated by interferon regulatory factor 4 (IRF-4), a lymphoid-restricted member of the IRF family of...
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Source: Immunotherapy Weekly (2003-04-16)
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