Immunotherapy Weekly

Inflammatory Disease - Researchers attribute transverse myelitis to chronic hepatitis C

Interstitial Pneumonia - Myofibroblast proliferation is more prevalent in collagen vascular disorder

Intestinal Diseases - Gastrointestinal stromal tumor found in patient with ulcerative colitis

Keratoacanthoma - Topical treatment with imiquimod induces regression or disappearance

Laser Scanning Cytometry - LSC revealed that tyrosine phosphorylation is deranged by diet restriction

Leukemia Therapy - HA-1- or HA-2-specific T cells can induce complete remission after relapse

Leukemia Therapy - Interleukin-2 with GM-CSF effective in mice

Liver Transplantation - A living donor strategy may improve the outlook for autoimmune hepatitis

Lupus Erythematosus - Abdominal pain may be the sole initial clinical presenting feature

Lymphoma - Data point to BCL-6 regulatory mechanism apart from transcriptional repression

Lymphopoiesis - Both ERalpha, ERbeta required for complete down-regulation of B lymphopoiesis

Macular Degeneration - A novel immunotherapy prevents the formation of choroidal neovascularization

Male Fertility - Interventions modulating epithelial function exploited to treat infertility

Memory T Cells - CD8+ central and effector subsets appear to have distinct origins

Meningitis - IL-16 may promote inflammatory responses with other proinflammatory cytokines

Moellerella Wisconsensis - Human and food isolates show natural antibiotic susceptibility and resistance

Monoclonal Antibodies - Laureate Pharma announces antibody manufacturing services agreement

Mucocutaneous Inflammation - Erythema multiforme encompasses intraoral lesions

Multiple Sclerosis - Combination therapy of beta-IFN and prednisone did not alter markers favorably

Multiple Sclerosis - Immunomodulatory IgG treatment in high doses may interfere with neurotropins

Myometrial Cells - Tumor necrosis factor alpha stimulates adenylyl cyclase activity

Myopericarditis - Recurrent myopericarditis can be a sign of inflammatory bowel disease

Non-Hodgkin Lymphoma - Automated CISH superior to IHC for light chain detection in PC dyscrasias

Opportunistic Infections - T-cell receptor Vbeta8.1 peptide may reduces coxsackievirus-induced heart damage

Opsoclonus-Myoclonus - Autoantigen diversity appears to be characteristic of the syndrome

Pain Medicine - N-3 polyunsaturated fatty acids may reduce pain by acting on the nervous system

Pancreas Transplantation - Macrophage-specific targeting signals independent of those received by T cells

Pancreatic Cancer - Virulizin shows activity against tumors in mouse model

Parkinson Disease - Microglia may be effector for selective degeneration of dopaminergic neurons

Patents - Therapeutic composition patent granted for Product R

Persistent Infection - Blood contains a low CD8 expressing T cell cytotoxic/effector subpopulation

Polymorphonuclear Leukocytes - CR3 antagonists block adhesion and adhesion-dependent oxidative burst in PMNs

Polymorphonuclear Neutrophil - PMNs express molecules required for antigen presentation and cell signaling

Pregnancy Cytokine - Fractalkine and cells bearing its receptor are present in amniotic fluid

Pregnancy Immunity - Decidual macrophages produce altered levels of immunosuppressive factors

Proteomics - PKC isoenzymes expressions are modulated in pancreatitis, pancreatic cancer

Pseudomonas Aeruginosa -  Pseudomonas aeruginosa aroA deletion mutants promising vaccine candidates

Psoriasis - Etanercept is a biologic approach to treatment of skin ailment

Psoriasis - Preliminary results suggest continued benefit of efalizumab

Radiation Exposure - Thyroid complications aren't present in nuclear test site neighbors' children

Renal Transplantation - Impaired immune response promotes accelerated atherogenesis in recipients

Rheumatoid Arthritis - Hypoxia induces glycolytic enzyme upregulation, creating inflammatory reaction

Septicemia - Hydrocortisone modulated immune response to stress by way of anti-inflammation

Skin Blistering - These rare autoimmune diseases of childhood require systemic immunosuppression

Staphylococcal Infection - Neutrophil seems to be main source of MRP8/14 in S. aureus infection model

Steroid Therapy Risk - Methylprednisolone treatment induced tumor lysis syndrome and renal failure

Stress Reaction - Hypoxia represses transcription by inducing negative cofactor 2 (Dr1/DrAP1)

Systemic Lupus Erythematosus - Anti-SSB/La autoantibody responsible for neutropenia and impairment of PMNs

T Cell Functions - CD7 marker concentration differentiates CD8 T cell subsets into functional sets

Thymocyte Apoptosis - All apoptotic events mediated by mitochondria are regulated by proteasomes

Tissue Regeneration - Expression profile of C3 and C5 supports nonimmunologic function of complement

Tumor Necrosis Factor - Company expands intellectual property related to its arthritis program

Vibrio Penaeicida Infection -  P. indicus females respond differently during ovarian development

Vitiligo - Tacrolimus ointment 0.1% induces partial repigmentation

Xeroderma Pigmentosum - Skin diseases reveal information useful to skin tumor research

Zoonosis - Diagnostic assays can now test for IgG to Crimean-Congo hemorrhagic fever virus