Allergic Asthma
Salbutamol use may increase eosinophil CXCL8 production, asthmatic response
Published in Immunotherapy Weekly, October 1st, 2003
"Regular salbutamol use can exacerbate allergen-induced airway eosinophilia in asthmatics, but its effect on airway eosinophil chemokine responses is unknown. Asthmatic subjects (n=14) were treated for 10 days with placebo or salbutamol in a double-blind, cross-over study, then given same-dose allergen challenges. Their sputa were then analyzed 1 and 7 h later for a panel of eosinophil-related cytokines," investigators in Canada report.
"Eosinophils from 5 test and 3 control subjects were tested for expression...
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Source: Immunotherapy Weekly (2003-10-01)
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