Immunotherapy Weekly

Immunology - The proinflammatory function of VEGF involves leukocyte regulation

Autoimmune Disease - Redundancy defines complex nature of cytokines and autoimmunity

Immunotherapy - Endoglin antibody works with transforming growth factor-beta to stop cancer

Infectious Disease -  H. pylori CagA mimicry may underlie cITP

Influenza Vaccine - Mistrust and fears of risk keep elderly from influenza vaccination

Leishmaniasis -  Leishmania donovani with BCG protects against leishmaniasis

Leishmaniasis -  Leishmania lesions affect nasal mucosa in rhesus monkey model

Leukemia Diagnostics - MRP3 linked to drug resistance in pediatric ALL

Malaria Vaccine - DNA vaccine elicits strong immune response against malaria sporozoites

Malaria Vaccine - Vaccines based on Plasmodium vivax Sal I strains show promise

Melanoma -  B. pertussis toxin induces T-cell responses against melanoma

Mycobacteria -  M. smegmatis GPLs inhibit macrophage phagocytosis

Ovarian Cancer - Administering topotecan weekly shows promise in the management of ovarian cancer

Patents - Vaccine company gets broad patent coverage for its core technology platform

Peripheral Arterial Disease - NCX 4016 successfully achieves primary efficacy endpoint in phase II study

Personnel - Biotechnology company announces new member to board of directors

Personnel - Company announces departure of CFO Gregory S. Patrick.

Poliovirus - Pan-pestivirus PCR primers cross-react with poliovirus genome

Research Funding - NIAID awards $12.95 million for biodefense contract

Rheumatoid Arthritis - Phase II clinical trial of LymphoStat-B for RA initiated

SARS - Company accelerates new oral SARS prevention program

Severe Combined Immune Deficiency - Unusual leukemia caused by rare combination of genes

Respiratory Syncytial Virus - Vaccine elicits immune response against respiratory syncytial virus

Stem-Cell Transplantation - CMV-seropositive donors might be preferable for seropositive SCT recipients

Stem-Cell Transplantation - Impaired naive T-cell survival underlies post-SCT immunodeficiency

Tuberculosis Diagnostics - PBMC-PCR can facilitate tuberculous lymphadenitis diagnosis

Tuberculosis Immunology - CD40 needed for efficient T-cell priming after M. tuberculosis exposure

Tumor-Activated Prodrugs - Cantuzumab mertansine and huN901-DM1 advance to proof-of-concept studies

Vaccine Efficacy - U.S. National Committee recommends strengthening vaccine supply

Adverse Drug Effects - Lamivudine prevents rituximab-induced hepatitis B virus reactivation

Allergy Medicine - Scientists identify genes that regulate allergic response to diesel fumes

Allergy Medicine - The bronchovideoscope detects increased vessel growth in new asthma patients