Immunotherapy Weekly

Drug Development - Conjugation with geldanamycin augments Herceptin antitumor activity

Drug Development - Mutant B-Raf peptide shows promise as anti-melanoma immunotherapy

Arthritis Therapy - Methods otrexate may be lymphoma trigger in patients with highly active RA

Breast Cancer Therapy - NMU-based murine model could aid search for immune-based treatment

Complementary & Alternative Medicine - Chinese herbal medicine credited with successful lung cancer treatment

Leukemia Therapy - Leukemic RNA-pulsed DCs induce anti-AML cytotoxic activity in vitro

Acute Promyelocytic Leukemia - CD2 expression by APL cells linked to poor prognosis

Adverse Drug Effects - Interferons used for treating multiple sclerosis raise liver enzyme levels

Allergic Rhinitis - R112 well tolerated in allergic rhinitis clinical trial

Allergies - FDA approves new chewable formulation of Zyrtec

Allergy Medicine - Eosinophil progenitors can migrate to airways

Allergy Medicine - Expert advice on delaying onset of childhood allergies may be flawed

Allergy Medicine - Gene silencing creates hypoallergenic plants

Allergy Medicine - New research on the treatment of anaphylaxis presented 2004 AAAAI meeting

Allergy Medicine - Variant CD14 allele linked to atopy in children, but not adults

Allergy Medicine - When it comes to allergies, Americans don't make the grade

Aneurysms - Company announces nanostructures in human aneurysms

Anthrax - Effects of anthrax lethal toxin reviewed

Anti-Infectives - Gemifloxacin inhibits cytokine release by LPS-stimulated monocytes

Arthritis - Aristospan availability announced

Arthritis Therapy - Infliximab can induce lupus erythematosus-like eruptions in RA patients

Asthma - Greater acetaminophen use associated with newly diagnosed asthma in women

Asthma - Positive results reported for Daclizumab phase II asthma trial

Asthma - Study: Increased IL-9 related to early asthma clinical changes

Atherosclerosis - Chlamydial LPS-specific IgG antibodies useful as sign of lesion infection

Autoimmune Disease - Researchers say chemo drug may help people with autoimmune diseases

Breast Cancer - MUC-1 in postoperative axillary drainage may indicate a poor prognosis

Breastfeeding - Global Strategy: Breastfeeding critical for child survival

Cancer Diagnostics - TCR-V-beta FACS can identify peripheral blood TCLPD involvement

Cancer Therapy - Merix Bioscience announces cancer vaccines agreement

Collaborations - Alliance targets development of arthritis, multiple sclerosis drugs

Crohn Disease - Interim results reported in phase II trial of Alequel

Cutaneous Lymphoma - HLA-G and IL-10 may contribute to disease severity

Dermatology - Pathogenesis of mid-dermal elastolysis elucidated

Dermatology - Skin distribution of TNF-alpha converting enzyme characterized

Diagnostics - IMPATH announces distribution agreement for QCA system

Diagnostics - LYVE-1 antibody recognizes lymphatic vessels in normal and pathological tissues

Drug Development - Novel HIV fusion inhibitor T-1249 safe, effective in early trials

Drug Development - Pegylated IFN-alpha effective as SARS prophylaxis in macaques

Dry Mouth - Salagen 7.5 mg tablet introduced

Finance - Biopharmaceutical company announces increased revenue in 2003

Finance - Biotech company reports 2003 net loss of $11.0 million

Finance - Specialty pharmaceutical company declares cash dividend

Genetic Test - Interleukin achieves milestone related to genetic testing agreement

HIV/AIDS Cancer - Bone marrow features in AIDS patients characterized

HIV/AIDS Genomics & Genetics - Effect of within-patient HIV mutation on population-level evolution clarified

HIV/AIDS Genomics & Genetics - Recombination dynamics of HIV genome determined

HIV/AIDS Immune Control - HIV-induced phenotype changes hamstring Gag-specific CD4 cells

HIV/AIDS Immune Control - HIV-infected lymphocytes modulate fibronectin output via TGFbeta1 secretion

HIV/AIDS Immune Control - Interaction between Leishmania and HIV clarified

HIV/AIDS Neuropathology - Effects of HAART on CNS disorders elucidated

HIV/AIDS Neuropathology - Murine spatial learning and long-term potentiation disrupted by HIV Tat

HIV/AIDS Pathogenesis - Thiol/disulfide exchange needed for R4 HIV T-cell fusion during viral entry

HIV/AIDS Therapy - Lipid profiles induced by different antiretroviral drugs characterized

HIV/AIDS Tuberculosis - Effects of HIV/TB coinfection of mothers in poor areas clarified

HIV/AIDS Vaccine - AIDS vaccine to be tested on humans