Immunotherapy Weekly

HIV/AIDS Treatment - Retinol assessment in HIV infection evaluates vitamin A deficiency in former IDU

HIV/AIDS-Associated Infection - ADA in CSF limited utility for tuberculous meningitis diagnosis in HIV infection

Hantavirus Vaccine - Cross-reactivity among hantaviruses investigated

Healthcare Coverage - Healthcare corporation acquires Atlanta, Georgia-based hospice

Hemorrhagic Fever - Ribavarin therapy effective against Crimean-Congo hemorrhagic fever

Hepatitis B Vaccine - Postvaccination hepatitis B surface antigenemia explored

Hepatitis B Virus - Clevudine potent and tolerable in hepatitis B virus-infected patients

Hepatitis C Vaccine - Hepatitis C virus mutation affects proteasomal epitope processing

Hepatitis C Virus - Glycoprotein E2 has mechanistic features in common with class II fusion proteins

Hepatitis C Virus - HCV coinfection associated with higher risk of diabetes in HAART era

Hepatitis C Virus - Hepatitis C virus infection associated with increased risk of malignant lymphoma

Hepatitis C Virus - Peginterferon and ribavirin safe/effective in HCV-infected methadone patients

Hepatitis Vaccine - Anti-hepatitis A immune response found in renal transplant patients

Hepatitis Vaccine - HIV-infected patients should receive hepatitis B vaccination

Hepatocellular Carcinoma - MAGE-n peptide could be immunotherapy target

Human Papillomavirus - Vaccinating and screening for human papillomavirus reviewed

Immunizations - Travel immunizations reviewed

Immunoassay - Combination of antibody enables self-calibration, reduction of sample matrix effects

Immunology - Apoptotic cells plus hematopoietic grafts alter immune responses

Immunology - Blue-field entoptic assay can measure LPS-induced microvascular leukocytosis

Immunology - Centrosome autoantibodies may provide a link between infection, autoimmunity

Immunology - Cytokine mutations associate with recurrent HCV after liver transplantation

Immunology - Haploidentical donor T cells fail to facilitate engraftment

Immunology - Immunology of protein degradation by ubiquitin system reviewed

Immunology - Ineffective KIR/HLA-C allorecognition system may result in spontaneous abortion

Immunology - Novel method allows for selective adsorption of CD4+ T cells

Immunology - Peptide-treated peritoneal cells suppress uveoretinitis

Immunology - The selective COX-2 inhibitor DFU staunches tumor growth in mice

Immunology - Thioaptamers targeting NF-kappa B could stall pathological immune response

Infection - Memory CD8 T cells are fully functional in the absence of CD4 T cells

Information Technology - Internet service helps physicians participate in pay-for-performance programs

Legal Issues - Litigation brought relating to merger between specialty pharmacy, MIM Corp.

Leukemia - Arsenic trioxide, MEK1 inhibitor treatment appears useful in hematologic cancers

Liver Regeneration - C3 activation is a pivotal mechanism for liver regeneration after CCI4 injury

Lung Injury - Correlation of cyclophosphamide-induced neutropenia studied

Lymphangiogenesis - Lymphangiogenic growth factors or their inhibitors could treat human diseases

Lypodystrophy - PI substitution with abacavir in severe lipodystrophy markedly reduces lipolysis

Malaria Vaccine - DNA vaccine protected against malaria in African black-footed penguins

Male Genital Tract Infection - Influence of leukocytes and bacteria on semen studied

Measles Vaccine - Measles virus receptors reviewed

Medical Devices - Veterinary diagnostics testing kit for feline leukemia virus approved by USDA

Meningitis Vaccine - Prevalence of bacterial meningitis among children in Romania reported

Meningococcal Vaccine - Diversity in pathogenicity can cause outbreaks of meningococcal disease

Meningococcal Vaccine - Epidemiology of meningococcal disease in Switzerland reported

Microbicides - HIV topical microbicides entering clinical trials should be reevaluated

Microbicides - PSC-RANTES blocks R5 HIV infection in immature Langerhans cells

Monoclonal Antibodies - The antibody hF4-3C5 antagonizes VEGFR-3 to limit tubular morphogenesis

Multiple Myeloma - Recurrent translocation results in aberrant expression of MAFB

Multiple Sclerosis - CCL2 and CCR2 may have a limited role in early active multiple sclerosis

Multiple Sclerosis - High co-payments influence multiple sclerosis patients' medication choices

Muscular Dystrophy - New protocol may be applicable for study in myoblast transplantation

Neuroblastoma - IL-2 therapy augments antitumor activity of hu14.18-IL2 immunocytokine

Nutrition - Dermatitis-like symptoms seen in HR-1 hairless mice on low magnesium/zinc diet

Nutrition - Impact of nutritional issues on head and neck cancer needs more study

Oncocytic Adrenocortical Carcinomas - Four cases of oncocytic adrenocortical carcinomas studied

Oncology - Tumor VEGF levels can't predict the value of adjuvant breast cancer therapy

Oral Cancer - RCAS1 expression might be associated with progression of oral tumors

Organ Transplantation - Solid organ transplantation across the ABO histo-blood group barrier observed

Outbreaks - Method to estimate threshold parameter R_* reported

Ovarian Cancer - Australian researchers report first case of unusual cancer

Pain Medicine - Cannabinoids do not induce serious/relevant immunosuppression in humans

Pain Medicine - Intrathecal IL-1beta activates iNOS-NO cascade in rats

Pancreatic Cancer - Novel mechanism for TGF-beta found to be key in targeting MUC4 overexpression

Papillomavirus Vaccine - Three rabbit oral papillomavirus oncogenes characterized

Parasitiology -  G. lamblia encystation dependent on novel transglutaminase activity

Patient Education - Psychologist launches CDs to help patients lower anxiety during medical procedures

Personnel - Biopharma announces management appointments

Personnel - Gene-silencing company initiates planned expansion of its scientific staff

Personnel - Stem cell company retains Dr. Avraham Treves to consult on development efforts

Pertussis Vaccine -  Bordetella pertussis electrophoresis profiles characterized

Pneumococcal Vaccine - Oligosaccharide protein conjugates promising as pneumococcal vaccines

Pneumococcal Vaccine - Pneumococcal vaccine may be appropriate for lung transplant recipients

Prion Disease - Multiple antigenic peptides promote anti-prion antibodies

Product Licensing - Centocor extends license to HuCAL antibodies

Product Licensing - PER.C6 licensing agreement inked with Synergenics and Synco Bio

Pseudomonas - Transmissible P. aeruginosa in cystic fibrosis identified/characterized

Pulmonary Fibrosis - Data support role of innate immune response in pulmonary fibrosis

Pulmonary Fibrosis - Researchers examine role of CXCR3 in pulmonary injury, repair in vivo

Renal Transplantation - Genes linked to postischemic ARF identified in cadaveric kidneys

Respiratory Syncytial Virus - Novel protein expression strategy developed

Rheumatoid Arthritis - Enrollment completed for phase IIa study of MM-093 in rheumatoid arthritis

Rheumatoid Arthritis - Telomere erosion may be a link between HLA DR4 and RA

Rotavirus - G, P genotypes of rotavirus circulating in children with diarrhea

Rotavirus Vaccine - Edible vaccine produced in transgenic plants protects against rotavirus

Schistosomiasis - Schistosome transcriptome analysis at cutting edge reviewed

Schistosomiasis - Schistosome transcriptome reviewed

Sinus Surgery - MM-9 may be therapeutic target for healing quality after sinus surgery

Smallpox Vaccine - 'Non-take' responses in adults vaccinated with smallpox reported

Stem Cell Research - 17 Beta-estradiol enhances neuronal differentiation of embryonic stem cells

Stem Cell Research - 5-Azacytidine induces stem cells to differentiate into cardiomyocyte phenotype

Stem Cell Research - Cryopreserved cord blood fractions alternative source of mesenchymal stem cells

Stem Cell Research - Dose rate at which lethal dose of TBR is delivered does not augment SC homing

Stem Cell Research - FgFr1 required for the proliferation of hippocampal progenitor cells

Stem Cell Research - Known and novel transcripts overexpressed in hematopoietic stem cells identified

Stem Cell Research - Neural stem cells in the subventricular zone resilient to hypoxia/ischemia

Stem Cell Research - Over 1700 human embryonic stem cell-material interactions characterized

Stem Cell Research - Serum-free media improve generation of embryonic stem cells

Stem Cell Research - Strategy proposed for breast stem cells to ignore mitogenic effects of estrogen

Stem Cell Transplantation - Allogeneic stem cell transplantation is safe in elderly patients

Streptococcus Vaccine - Genome aids search for virulence determinants in Streptococcus uberis

Streptococcus Vaccine - Peptide antigen plays role in inducing Streptococcus mutans antibodies

Stroke - NRG-1 may provide a target for the development of new stroke treatments

Syphilis - Increased syphilis testing coincided with public health interventions

Syphilis Vaccine - Immunity of Treponema pallidum repeat protein subfamily determined

Testicular Cancer - CIS/ITGCNU arises from developmentally arrested germ cells

Tetanus Vaccine - Reduction of anti-tetanus antibody by tetanus toxoid peptides reported

Transplant Medicine - Cyclosporine A and PI interactions in liver transplantation can be managed

Transplant Medicine - Patented process preserves transplant tissues/organs

Tuberculosis - Financial difficulties influence TB care-seeking behavior in rural China

Tuberculosis Vaccine - Prevalence and diversity of M. tuberculosis arabinomannan reported

Vaccine Adjuvant - Cholera toxin prevents autoimmune disease by inducing immune deviation

Vaccine Adjuvant - CpG motifs are efficient adjuvants for DNA cancer vaccines

Vaccine Development - Recombinant viruses induce protective cellular immunity

Vaccine Efficacy - Adult vaccination update released

Vaccinia Vaccine - Generalized vaccinia in a deployed military member reported

Viral Evolution - Cross-reactive immunity leads to viral evolution, which limits extent of disease

Virology - Virus-induced neuronal apoptosis in the CNS may be a pathological host response

Virology Vaccine - FIV glycoprotein antibodies not responsible for infection in cats

Virology Vaccine - Host-pathogen interactions provide insights into Marek disease vaccines

Virology Vaccine - Surface expression of Newcastle disease virus proteins studied

Wiskott-Aldrich Syndrome - Probing the surface of white blood cells enhances immune system medicine

Wound Therapy - Matrix metalloproteinase-2, MM-9 involved in wound healing