Published in Immunotherapy Weekly, October 13th, 2004
According to recent research published in the journal Vaccine, "Secondary lymphoid chemokine (SLC) attracts mature dendritic cells (DCs) and naive T cells. Co-localization of these cells within local tumor environments may enhance the induction of tumor-specific T cells. However, the presence of danger signals or other DC maturation signals are required to optimize T-cell priming. We hypothesized that expression of SLC in vaccinia virus would provide local chemokine delivery and adjuvant factors. A recombinant vaccinia...
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