Immunotherapy Weekly

HIV/AIDS-Associated Infection - Cryptococcal meningitis decreased/cerebral toxoplasmosis increased in HARRT era

HIV/AIDS-Related Drug Interaction - Nevirapine reduces racemic methadone/(R)-methadone levels in HIV infection

HIV/AIDS-Related Neuropathogenesis - Astrocyte dysfunction contributes to HIV Tat neurotoxicity

Haemophilus Vaccines - Studies add new findings to haemophilus vaccines body of knowledge

Haploidentical Stem Cell Transplantation - Automated graft processing devices ensure feasibility of haploidentical SCT

Haploidentical Stem Cell Transplantation - Haploidentical parental donor viable option for children lacking identical donor

Helicobacter Pylori -  H. pylori cag pathogenicity island disrupted in majority of patient isolates

Helminth Vaccine - Dendritic cell maturation by Nippostrongylus proteins drives immune response

Hematopoiesis - EDAG regulates proliferation and differentiation of hematopoietic cells

Hemoglobin - Tandem mass spectrometry identifies serum cross-linked hemoglobin

Hepatitis B Therapy - Study shows peginterferon alfa-2b effective monotherapy for chronic hepatitis B

Herpesvirus - HMGB1 facilitates RTA-mediated viral gene expression in gamma-2 herpesviruses

Herpesvirus - Murine gammaherpesvirus 68 glycoprotein B processing similar to KSHV gB & CMV gB

Huntington Disease - Companies establish collaboration to develop treatment for Huntington disease

Hypertension - Drug maker notes risk of OTC decongestants in high blood pressure sufferers

Immunodeficiency - Antibodies to Haemophilus and Streptococcus in IGIV products detected

Immunology - Anti-CD2 antibody BTI-322 has potential as tolerogenic agent

Immunology - Antigen concentrates in small number of antigen presenting cells

Immunology - Generation and maintenance of immunological memory reviewed

Immunology - Immunity to extracellular domain of Nogo-A modulates encephalomyelitis

Immunology - Kinetics and clonality of immunological memory in humans reviewed

Immunology - Protein's role in immune defense uncovered

Immunology - Reports add new data to immunology research

Immunology - Terminal complement complex involved in vascular leakage

Immunology - Transporter for antigen processing preselection of peptides binding evaluated

Immunoreactivity - Eosinophils regulate T cell subset selection through indoleamine 2,3-dioxygenase

Immunotherapy - Immune regulation via CD1d-dependent NKT cells reviewed

Infectious Disease Research - Company awarded $24 million to study genetics of infectious disease and vaccines

Influenza - RT-PCR using primers based on HA2 gene detects all 15 HA influenza A subtypes

Influenza Vaccine - Attenuated influenza vaccine induces cross-reactive antibody responses

Influenza Vaccine - Data from Vaxin's first flu vaccine clinical trial reported

Influenza Virus - Transmissibility of 1918 pandemic influenza reviewed

Lactase - Real-time PCR quantifies bovine lactase mRNA from GI tract of milk-fed calves

Listeria Monocytogenes - Mixed-genome DNA microarray identifies L. monocytogenes serotypes & subtypes

Lymphocytic Choriomeningitis Virus - Antigen-independent T cells do not develop during chronic viral infection

Lymphocytic Choriomeningitis Virus - CCR7 not required for maintaining antiviral memory

Lymphoma - Stem cell transplants viable option for patients suffering from lymphoma and HIV

Malaria Vaccines - Researchers detail new studies and findings in the area of malaria vaccines

Malignant Melanoma - Phase I clinical trial begins using MedPulser System

Marine Parasite - Real-time PCR detects/quantifies Perkinsus marinus in environmental waters

Medical Devices - Visual-diagnosis software guides treatment of skin ailments

Melanoma - Recent studies add new data to melanoma research

Melanoma Vaccine - Mouse MAGE-derived H-2K^b-restricted CTL epitopes characterized

Methicillin-Resistant Staphylococcus Aureus - EMSRA strain tracked from one hospital as it spread to surrounding hospitals

Methicillin-Resistant Staphylococcus Aureus - Joint cooperation controls MRSA outbreak involving several hospitals

Multiple Sclerosis - Researchers' work adds to multiple sclerosis body of knowledge

Mycobacterium Tuberculosis -  Mycobacterium tuberculosis Cameroon family is molecularly characterized

Mycobactetium Brumae -  Mycobactetium brumae caused catheter-related bloodstream infection

Myocarditis - Immunoglobulins suppress autoimmune myocarditis in immunodeficient mice

Natural Products - Global experts cite emerging health benefits of probiotics

Neural Stem Cell Research - Differentiated neural stem cells express functional glial glutamate transporters

Neural Stem Cell Research - Distinct neural precursors in developing spinal cord developmentally regulated

Neural Stem Cell Research - Fetal neural progenitors can be the target for tumor transformation

Neural Stem Cell Research - GM-CSF has potential role in neural development or repair

Neural Stem Cell Research - NSCs promote injured motor neuron survival through neurotrophic factor secretion

Neural Stem Cells Transplantation - Transplanted neural stem cells to contused brain express only MHC-II antigens

Neurogenesis - Ascorbic acid increases gene expression involved in neurogenesis

Neuroscience - A-beta specific antibody reduces beta-amyloid in Alzheimer model

Nocardiosis -  Nocardia nova caused sporotrichoid nocardiosis in HIV-infected patient

Norovirus - SDS/EDTA-pretreated chromatography paper strips used for Norovirus sampling

Obesity - Gut microbiota regulates fat storage in the host

Orthopedic Surgery - Novel approach enables effective management of hemophiliacs with inhibitors

Osteoarthritis - Pain relief company unveils service to address knee pain from osteoarthritis

Pancreatic Cancer - New findings in the area of pancreatic cancer detailed

Pancreatitis - Recurrent pancreatitis misdiagnosed as familial Mediterranean fever

Papillomavirus - Nested PCR with PGMY09/11 and GP5+/6+ primer sets improves HPV DNA detection

Patents - Biotechnology company files citations relevant to Benitec patent

Patents - CollaGenex seeks immediate injunctive relief to enforce its patent

Personnel - Biothrax maker names Dr. Steven Chatfield named chief scientific officer

Personnel - Ronald C. Newbold elected operations executive VP of biotech holding company

Pharmaceutical Research - Dutch company enters kinase target drug screening markets through new agreement

Pneumococcal Vaccine - Antibodies elicited by conjugates of pneumococcal polysaccharide compared

Pneumococcal Vaccine - Weight-based antibody units assigned for antipneumococcal reference serum

Pneumocystis Carinii Therapy - Piperazine-linked bisbenzamidines active against Pneumocystis carinii

Pneumonia - Cytomegalovirus pneumonia not associated with bronchiolitis obliterans syndrome

Polio Vaccine - Poliovirus revaccination elicits long-term immunity in stem cell recipients

Poxvirus Vaccine - Cellular source of poxviral N1R/p28 gene family identified

Preventive Medicine - Clinical pharmacy travel medicine services reviewed

Product Licensing - Corixa licenses novel target for therapeutic development and commercialization

Product Licensing - Therapeutics company licenses DISC-HSV and DISC-GM-CSF vector platforms

Pseudomonas Aeruginosa - Carbapenem-resistant Pseudomonas aeruginosa outbreak strain produced VIM-8

Public Health - Public vaccination policies for containing anthrax outbreak outlined

Receptor Studies - Polymeric Ig binding fragment of polymeric Ig receptor characterized

Reproductive Medicine - Dietary copper supplement prevents adverse sperm effects produced by TTM

Reservatrol - Resveratrol-induced apoptosis in prostate cancer cells mediated by PKC-alpha

Respiratory Medicine - Antisense molecules block asthmatic reactions in mice

Retinal Stem Cell Research - Eye contains cells with retinal stem-cell characteristics

Rheumatoid Arthritis - Collagen-specific T cells tracked in collagen-induced arthritis

Rheumatoid Arthritis - Company's first phase 1 study evaluates safety of rheumatoid arthritis treatment

Rheumatoid Arthritis - Osteoblast protein induction studied, role of methotrexate revealed

Rotavirus Vaccine - Antibody responses in calves and piglets infected with rotavirus reported

SARS Outbreak - Strict infection control is an effective intervention following SARS exposure

SARS Vaccine - Replication of SARS coronavirus in monkey respiratory tract investigated

SARS Vaccine - SARS-CoV vaccine elicits antibodies that block virus entry

SARS Vaccines - New findings in SARS vaccines described

SARS Vaccines - New findings in the area of SARS vaccines detailed

Sexual & Reproductive Health - Vaginal antibacterial, antifungal products licensed for marketing in Mexico

Skeletal Tuberculosis - Skeletal tuberculosis may be suspect in cases of long-standing pain and swelling

Smallpox Vaccine - Voluntary smallpox vaccination requires information about attack likelihood

Stem Cell Research - Fgf4 expression induced by transforming growth factor beta-related protein Nodal

Stem Cell Transplantation - Endocarditis following HSCT is associated with a high mortality rate

Stem Cell Transplantation - HSCT survivors have increased risk of secondary nonhematologic malignancies

Stem Cell Transplantation - Hyponatremia and SIADH are common complications following SCT

Stem Cell Transplantation - NK cell immunotherapy is used to treat AML patients following HSCT

Stem Cell Transplantation - Standard IV busulfan dose in children may not fall within AUC reference range

Stem Cell Transplantation - T-cell-depleted megadose SCT from mismatched donor viable option for adults

Stem Cell Transplantation - Trimetrexate/denileukin diftitox depletes T cells from PBMC/UCB grafts

Streptococcus Vaccine - Antigenic determinants of alpha-like proteins of Streptococcus examined

Streptococcus Vaccine - Immunogenic proteins released from Streptococcus agalactiae identified

Systemic Lupus Erythematosus - Company introduces new platform for autoimmune disease drug discovery

Systemic Lupus Erythematosus - Genes in the interferon system important in SLE

Systemic Lupus Erythematosus - Headache is more common in SLE patients than in rheumatoid arthritis patients

Systemic Lupus Erythematosus - Insights into IFN/lupus connection yield diagnostic, therapeutic opportunities

Systemic Lupus Erythematosus - Migraine in systemic lupus erythematosus studied, role in organ damage clarified

Transfusion Medicine - Improving technology helps in collecting platelets by apheresis

Tuberculosis - Company announces breakthrough in treatment of TB and MDR-TB

Tuberculosis Vaccine - Vgamma T cell stimulation optimizes TB vaccine-induced CD8 T cell immunity

Tularemia Vaccine - IglC expression needed for apoptosis in macrophages by Francisella

Umbilical Cord Blood Research - Neural markers elevated during acute differentiation of UCB-derived cells

Umbilical Cord Blood Transplantation - Unrelated UCB transplant alternative option to HSC in children and adults

Vaccine Delivery - Antigen-specific B lymphocytes regulate delivery of therapeutic proteins

Vaccine Development - Combined vaccines synergize to resist cancer growth

Vaccine Development - Lipopeptide epitopes trigger Th1-dependent protective immunity

Vaccine Efficacy - Contraction phase of viral T cells unaffected by pan-caspase inhibitor

Vaccine Efficacy - Dietary ribonucleotides affect infant humoral immune status

Vaccine Efficacy - Statistical tests to determine vaccine efficacy evaluated

Vaccine Safety - Child with itching nodule receives aluminum-containing vaccine safely

Vaccines Development - Researchers describe findings in vaccines development studies

Vaccinia Virus - Protein interactions among vaccinia virus transcription factors described

Vibrio Parahaemolyticus - KP+/TDH+ environmental V. parahaemolyticus strains isolated

Virology - Antiviral immunity requires Toll-like receptor signaling

Virology - Liposomal peptide vaccine primes T cells against cells bearing HCV protein

Water Contamination - Household storage practices increase water contamination in India

West Nile Virus Vaccine - Attenuated West Nile prototype virus protects against deadly NY99 strain