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SARS

Novel monoclonal antibodies neutralize SARS coronavirus in vitro

Published in Immunotherapy Weekly, April 6th, 2005

Novel monoclonal antibodies (mAbs) targeting key SARS coronavirus (SARS-CoV) proteins have been shown to neutralize the virus in vitro.

The availability of SARS-CoV-specific mAbs "is important for the development of both diagnostic tools and treatment of infection," immunologists in Canada explained.

In their study, M.J. Gubbins and coauthors at the National Microbiology Laboratory in Winnipeg evaluated "nine monoclonal antibodies raised in immune mice, using highly purified, inactivated SARS-CoV as the inoculating antigen."

"These antibodies are specific for numerous viral protein targets, and six of them are able to effectively...

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