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Immunotherapy Weekly

Susan Hasty, Publisher

Table of Contents . . . April 20th, 2005

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Immunotherapy Weekly | Other Publications

Allergy and Immunology - Vaccine containing CpG oligodeoxynucleotides heighten immune activation

Arthritis - Inactivity due to arthritis does not cause obesity

Avian Viral Vaccines - RT-PCR used to detect reovirus contamination in avian viral vaccines

Rabies Vaccine - Adverse reactions to Thai Red Cross Society rabies vaccine reported

Vaccine Development - Predefined spacers between epitopes for vaccine development constructed

Acute Myeloid Leukemia - Criteria for defining complete remission re-evaluated

Acute Pancreatitis - Hydrogen sulfide plays key role in inflammation and lung injury

Addiction Medicine - Tumor necrosis factor antisense therapy fights alcoholic liver disease

Adenovirus Vaccine - Adenoviruses are emerging pathogen in immunocompromised patients

Alcohol Use - Long-term ethanol intoxication impairs rat inflammatory responses

Allergens - Novel isoforms of Pru av 1 identified, diverging IgE binding revealed

HIV/AIDS Therapy - Researchers publish new studies and findings in the area of HIV/AIDS therapy

Allergic Rhinitis - Data announced on ragweed allergy immunotherapy clinical trial information

Allergic Rhinitis - Latest developments in management of allergic rhinitis reviewed

Allergy & Immunology - Advances in immunotherapy for allergies presented

Allergy & Immunology - Budesonide nasal washing may decrease symptoms in chronic hyperplasic sinusitis

Allergy & Immunology - Differences in IgE levels found between parents and their children

Allergy & Immunology - Dynavax regains rights to seasonal allergy program

HIV/AIDS Vaccines - Recent findings illuminate research in HIV/AIDS vaccines

Allergy & Immunology - Novel therapy tested in mice could chase away cat allergies

Allergy & Immunology - Phase I data presented on allergy medication

Allergy & Immunology - Researchers develop model to study food allergy-induced asthma

Allergy & Immunology - Researchers discover possible preventative target against atopic disease

Allergy & Immunology - Researchers show immune mechanisms after SLIT treatment

Allergy Medicine - Dok-1 mediates antiallergic activity of dexamethasone

HIV/AIDS Vaccines - Studies add new findings to HIV/AIDS vaccines body of knowledge

Allergy and Immunology - A splice site mutation points to X-linked chronic granulomatous disease

Allergy and Immunology - Chimeric constructs generate recombinant IgE antibody upon transfection

Allergy and Immunology - Mimicry by hepatitis C virus envelope protein E2 allows immune escape

Anthrax - Anthrax spores cleared from lungs between 8-14% per day

Anthrax Vaccines - Reports advance knowledge in anthrax vaccines research

Apoptosis - Homeobox Msx1 interacts with p53 and inhibits tumor growth via apoptosis

HIV/AIDS Vaccines - Studies advance knowledge in HIV/AIDS vaccines research

Apoptosis - Macrophage physiology in bacterial clearance studied, Mcl-1 expression defined

Apoptosis - PrP studied, influence on neuronal SOD activity revealed

Arthritis - Changes in the pericellular matrix with osteoarthritis has important influence

Arthritis - Collagen compound study shows reduced arthritis-related pain, lameness in dogs

Arthritis - Enzyme discovery brings new hope for arthritis cure

Arthritis - Top anti-arthritis drugs cause skin disease

Malaria Vaccines - Researchers detail new studies and findings in the area of malaria vaccines

Asthma - Asthma treatment shows low incidence of side effects in pediatric patients

Asthma - Earlier use of budesonide lowers asthma-related events in children, study shows

Asthma - Research in childhood and adult asthma featured at academy meeting

Asthma - Study shows who is likely to have asthma attack, go to emergency room

Asthma - Study: Fewer children with asthma who used nebulized ICS early were hospitalized

Atherosclerosis - T-bet deficiency studied, effects on atherosclerosis and immune responses shown

Oncology - Reports describe recent advances in oncology research

Awards - Vaccine researchers receive Discoverers Award from pharmaceutical industry

Bioterrorism -  Burkholderia species should be considered as possible agents of biowarfare

Bioterrorism - Biotech company presents research on treatment for acute radiation sickness

Bioterrorism - Data: ISS-based vaccine may represent new approach for anthrax immunity

Blood Substitute - Hemoglobin blood substitute used in critically anemic Jehovah Witness

Breast Cancer - Antigen Express initiates clinical trials in Her-2/neu positive breast cancer

Oncology - Research in oncology provides new insights

Breast Cancer - Data advance knowledge in breast cancer research

Breast Cancer - Identification of target genes directly regulated by SRC-3/AIB1 coactivator

Breast Cancer - New drugs contribute to neoadjuvant treatment of early breast cancer

Business & Finance - Genetics company reports on "solid progress" during second quarter

Business Update - Allergy medicine company taps Cappello Capital Corp.

Business Update - Drug companies launch and comarket pediatric antiallergic syrup in Japan

Oncology - Researchers' data advance oncology research

Business Update - Immunology-focused biotechnology company updates clinical development plans

Business Update - SinusPharma changes name to reflect focus on chronic rhinosinusisitis treatments

Cancer Cell Apoptosis - LDOC1, a novel MZF-1-interacting protein, induced apoptosis

Cancer Drugs - Synthetic chalcones used as anti-inflammatory and cancer chemopreventive agents

Cancer Prevention - Claudin-4 may mediate chemopreventive effects of NSAIDs

Cancer Prevention - Oltipraz-regulated hepatocyte genes identified

Oncology - Studies advance knowledge in oncology research

Cancer Risk Factors - Hepatitis B and C coinfection heightens one's risk for developing liver cancer

Cancer Risk Factors - Viral hepatitis and aflatoxin biomarkers predict liver cancer risk

Cancer Therapy - Apoptotic effects of D-24851 on glioma cells characterized

Cancer Therapy - Avian embryo models highlight the key steps of human tumor progression

Cancer Therapy - Metal bonding domain of Fe(II)-bleomycin characterized

Cancer Therapy - Patient recruitment completed for phase IIb Pentrys trial

Oncology - Studies describe new findings in oncology research

Cancer Vaccines - Antibodies against cancer reviewed

Cancer Vaccines - Majority of women accept cervical cancer vaccine for self, children, study shows

Cancer Vaccines - Recent findings in cancer vaccines provide new insights

Chemokines - Chemokine IL-8 analyzed, influence in human microglia revealed

Chickenpox Vaccine - Preventing varicella-zoster disease reviewed

Chronic Myeloid Leukemia -  IFITM1 expression has prognostic value

Cloning - Muslims distinguish between reproductive and therapeutic cloning

Colitis - Oxytocin a potential therapeutic agent in colonic inflammation

Collaborations - Domantis announces alliance to discover dAbs for autoimmune diseases

Collaborations - Pharma companies announce drug discovery and development collaboration

Collaborations - Research collaboration with International AIDS Vaccine Initiative announced

Colon Cancer Prevention - Green vegetables may decrease colon cancer risk

Colorectal Cancer - Cytomegalovirus not associated with colorectal tumorigenesis

Colorectal Cancer - Pharmacokinetics of 99mTc-labeled antibody in cancer patients reported

Coronavirus Vaccine -  Lactobacillus expressing coronavirus protein induces antibodies

Cryptosporidiosis - Cryptosporidiosis declines after membrane filtration of public water supply

DNA Vaccine - Aleutian mink disease gene partially protects against disease

DNA Vaccine - TLR9 pathway involved in adjuvant effects of plasmid DNA-based vaccines

DPT Vaccine - Aluminum content affects immunogenicity of DTP vaccine in adolescents

Dendritic Cell Vaccine -  Neisseria proteoliposomes interact with dendritic cells

Dendritic Cell Vaccine - Antigen-specific Th1 responses limited in ability to inhibit Th2 cells

Diagnostics - Device company reports success in resolving saliva test difficulties

Diagnostics - U.S. FDA clears Hycor Biomedical autoimmune test for diagnosing celiac disease

Diagnostics Imaging - Research add new data to diagnostics imaging body of knowledge

Diphtheria Vaccine - Boost unnecessary in individuals with long-term diphtheria protection

Drug Development - Alvesco provides relief of asthma symptoms comparable to budesonide, fluticasone

Drug Development - Aspirin-derived cobalt-alkyne complexes have antitumor, anti-COX activity

Drug Development - Asthma data on inhaled antisense drug presented

Drug Development - Humanized immunoenzyme targets B-cell lymphoma

Drug Development - Novel indolylquinols have significant antitumor activity

Drug Development - The antihistamine mizolastine has antiangiogenic properties

Drug Development - Topical FK506 after keratoplasty may be effective as immunoprophylaxis

Drug Microencapsulation - PEG-coated lipid microspheres improve indomethacin delivery in arthritic rats

Ebola Outbreak - Wild animal mortality monitoring predicts human Ebola outbreaks

Embryonic Development - HSCs restricted in their differentiation potential during embryo development

Embryonic Stem Cell Research - Embryonic stem cells are a source of dendritic cells for clinical applications

Embryonic Stem Cell Research - Two independent anatomical sites generate hematopoietic cells

Endocrinology - Putative tumor suppressor DMBT1 is estrogen-regulated in uterus

Environmental Health - Mechanism of dicyclanil-induced hepatocarcinogenesis determined

Enzymology - Analysis of Ostertagia ostertagi metalloproteases described

Enzymology - Inducible caspase-9 disrupts neovascular growth after adenoviral delivery

Enzymology - Structure of Rhodothermus marinus cytochrome c domain determined

Enzymology - Studies advance knowledge in enzymology research

Esophageal Cancer - HGF receptor c-Met overexpressed in esophageal adenocarcinoma

Finance - Connetics announces offering of $150 million of 2.0% convertible senior notes

Finance - Food and animal safety products company reports third quarter results

Fitness and Wellness - Physical fitness fights stress

Food Allergy - New approaches for treatment of peanut allergy reviewed

Gastric Cancer - Cyclin E overexpression with p53 expression may indicate poor prognosis

Gastroenteritis Virus Detection - RT-PCR-based dot blot hybridization detects/differentiates PEDV and TGEV

Gastroenterology - Intraperitoneal antisense K-ras RNA suppresses pancreatic cancer dissemination

Gastrointestinal Surgery - Modified stapling technique improves outcome of distal gastrectomy

Gene Research - BRCA2 knock-down exposes its potential to control alternate mechanisms

Gene Research - Data mining and PCR divulge genetic signatures linked to therapeutic effects

Gene Research - Doublecortin gene is a molecular marker for neuroblastoma residual disease

Glioblastoma - Integrated DNA- and mRNA-based tumor profiles reveal novel subtypes

Glioblastoma Multiforme - Recombinant targeted toxin TP-38 can produce sustained response

Glioma Therapy - Rottlerin sensitizes glioma cells to TRAIL-induced apoptosis

Glioma Therapy - Sequential high-dose chemotherapy suitable for pediatric patients

Gonorrhea - New findings in the area of gonorrhea described

HIV/AIDS - Preliminary data released in AIDS clinical trial

HIV/AIDS Biotechnology - LC/MS assay quantities NRTIs in biological matrices

HIV/AIDS Coinfection - Interactions between HIV and herpes viruses occur within the oral mucosa

HIV/AIDS Drug Adherence - Medication adherence training instrument assists persons living with HIV/AIDS

HIV/AIDS Drug Development - Betulinic acid derivatives inhibit HIV-1 fusion/interfere with HIV-1 maturation

HIV/AIDS Drug Development - Cellular deoxyhypusine synthase is a target for antiretroviral therapy

HIV/AIDS Drug Development - Pyridine N-oxide derivatives protects against HIV-induced CD4 cell destruction

HIV/AIDS Drug Resistance - HIV-1 mutations associated with reduced susceptibility identified in Brazil

HIV/AIDS Epidemiology - HLA-A11 associated with CTL response against HIV-1 Nef in exposed persons

HIV/AIDS Healthcare - Case management/shared-care schemes provide integrated care for HIV/AIDS

HIV/AIDS Pathogenesis - Endocytosis contributes to productive HIV entry

HIV/AIDS Pathogenesis - Heterogeneous selective pressures in env gene evolution among HIV-1 subtypes

HIV/AIDS Pathogenesis - Major coreceptors of HIV-2 variants identified from persons with/without viremia

HIV/AIDS Pathogenesis - Myristoyl moiety of HIV Nef involved in regulation of calmodulin interaction

HIV/AIDS Pathogenesis - Recent findings in HIV/AIDS pathogenesis provide new insights

HIV/AIDS Pathogenesis - Rodent cells support key functions of HIV-1 Nef

HIV/AIDS Pathogenesis - VCAM-1 expression on CD8+ cells correlates with enhanced anti-HIV suppression

HIV/AIDS Pathogenesis - Vif defects yield hypermutated genome that integrates but cannot produce progeny

HIV/AIDS Research - Covalent fusions with SlyD or FkpA solubilize retroviral Env proteins

HIV/AIDS Research - Researchers detail new studies and findings in the area of HIV/AIDS

HIV/AIDS Research - SP1 sequence mutation impairs HIV-1 Gag multimerization/membrane-binding

HIV/AIDS Research - Strong genetic signature exists for HIV-1 replication in male genital tract

HIV/AIDS Therapy - Australian "OPAL" provides hope for HIV treatment

HIV/AIDS Therapy - CSF HIV is an accessible surrogate for HIV virions in brain

HIV/AIDS Therapy - IL-7 induces latent HIV-1 cellular reservoirs of infected individuals on HAART

HIV/AIDS Therapy - Lymphocyte activation + RT inhibitors protect against retroviral disease

HIV/AIDS Therapy - Researchers provide details of new studies and findings in the area of HIV/AIDS therapy

HIV/AIDS Vaccine - Antigen with enhanced specificity for HIV antibody developed

HIV/AIDS Vaccine - BCG Env V3 elicits protection against SHIV with homologous V3 motif

HIV/AIDS Vaccine - Correlates of HIV vaccine trial participation in India reviewed

HIV/AIDS Vaccine - Epidemiological contribution to HIV vaccine field trials reported

HIV/AIDS Vaccine - HIV-1 vectors produced from stable packaging cells

HIV/AIDS Vaccine - Polyethylenimine-plasmid complex induces gp120-specific immune response

HIV/AIDS Vaccine - SIV inactivated by N-ethylmaleimide with preservation of functional Env

HIV/AIDS Vaccine - Tat-neutralizing versus Tat-protecting antibodies investigated

HIV/AIDS Vaccine - Vaccinia virus expression of gp120 and EGFP in host cell lines studied

HIV/AIDS Vaccines - Companies, UMMS announce phase I HIV vaccine trial enrollment completion

HIV/AIDS Vaccines - Data advance knowledge in HIV/AIDS vaccines research

HIV/AIDS Vaccines - Stanford study finds HIV drug resistance assay superior to Virco's Antivirogram

HIV/AIDS-Related Metabolic Syndrome - Lipid-lowering drugs may cause pharmacokinetic interactions with antiretrovirals

HIV/AIDS-Tuberculosis Coinfection - Fas/Fas-ligand has role in immune modulation and pathogenesis of tuberculosis

HIV/AIDS-Tuberculosis Coinfection - Peripheral lymph node needle-core biopsies diagnose TB in HIV-infected adults

Head & Neck Cancer - TAP1 and TAP2 allele frequencies analyzed in a SNaPshot

Hematology - Advances made in chronic refractory immune thrombocytopenic purpura therapy

Hematology - Stimulation of platelet production may provide a new management option for ITP

Hepatitis C - Study initiated to evaluate hepatitis C infection post liver transplant

Herpesvirus Vaccine - Bovine herpesvirus enhances efficacy of DNA vaccine in cattle

Idiopathic Pulmonary Fibrosis - Volunteers needed for university study of idiopathic pulmonary fibrosis

Immune Activation - T cell defects arise from chronic Ag activation leading to rapid CD8+ cell aging

Immunology -  Borrelia burgdorferi analyzed, cross-reactivity of antibodies revealed

Immunology - Anti-CD3 antibodies induce proliferation of T cells

Immunology - Autoimmune encephalomyelitis studied, effect of amino acid changes clarified

Immunology - Cytokines and types of inflammatory cells expressed differently in HPV and HIV

Immunology - Glial fibrillary acidic protein studied in trigeminal and dental tissues

Immunology - Lymphoid depletion is a practical strategy of liver transplantation

Immunology - Myasthenia gravis studied, unique immune recognition pattern revealed

Immunology - Roles of MyD88 and TRIF in LPS-induced gene expression clarified

Immunology - Scientists shed new light on role of natural killer T cells in fighting disease

Infant Mortality - Second-born very low birth weight twins risk increased respiratory morbidity

Inflammatory Bowel Disease - Research needed to assess efficacy of GA in inflammatory bowel diseases

Influenza A Virus - Avian influenza A subtype H7-infected pigeons multiply and excrete H7 viruses

Influenza Vaccine - Antibody levels against denatured influenza virus reported

Influenza Vaccine - Population-wide benefits of influenza vaccination in children outlined

Influenza Vaccine - Vitamin E affects immune response to influenza vaccine in elderly

Information Technology - Life sciences and high technology company releases brochure on ion channels

Kidney Transplantation - Delayed graft function indicates immune activation

Lactose Intolerance - Fast-acting dietary supplement for lactose intolerance launched

Leishmaniasis - 71 strains from cutaneous leishmaniasis in Tunisia characterized

Leukemia - Genetically modified natural killer immune cells attack, kill leukemia cells

Lung Cancer Therapy - Potent CDC25 inhibitors synthesized

MMR Vaccine - intervention improves MMR vaccination coverage in immigrant children

Malaria Vaccines - Reports add new data to malaria vaccines research

Matrix Metalloproteinase - Matrix metalloproteinase studied, role in amyotrophic lateral sclerosis revealed

Medulloblastoma Therapy - Cranial irradiation linked to impaired white matter development in children

Melanoma Vaccines - Data advance knowledge in melanoma vaccines research

Mergers & Acquisitions - Acquisition of Research Diagnostics Inc by biotech company completed

Monoclonal Antibodies - Antibody recognizes distinct epitope of human CD40 molecule

Myasthenia Gravis - Peripheral blood lymphocytes studied, response in myasthenia gravis clarified

Mycobacterium Detection - Staining parameters determined to increase sensitivity of mycobacterial smears

Mycobacterium Diagnosis - PCR identifies nontuberculous mycobacteria from paraffin-embedded tissues

Mycobacterium tuberculosis - DC-SIGN differentiates between pathogenic and nonpathogenic mycobacteria

Myelodysplastic Syndrome - Darbepoetin alpha suitable for anemia treatment in low-intermediate risk MDS

Neural Stem Cell Research - Estrogen promotes differentiation/survival of NSC-derived dopaminergic neurons

Neurocytoma - Optimal treatment for well-differentiated neurocytoma elucidated

Neuroscience - Microvascular compartment gene profiles define autoimmune encephalomyelitis

Neurotransmitter - Neurotransmitter conjugate activates membrane receptors

Nocardia brasiliensis - Patients with N. brasiliensis actinomycetoma have type Th2 immune response

Nutrition - Dietary fatty acids ameliorate heightened inflammatory cytokines

Oncogenesis - New findings in the area of oncogenesis described

Oncology - Antibody to podoplanin differentiates tumor-associated lymphangiogenesis

Oncology - Environmental factors modify genetic susceptibility to primary liver cancer

Oncology - Findings describe new data in oncology research

Oncology - Livin/ML-IAP shows promise as target antigen for lung cancer vaccine

Oncology - NF-kappaB and IkappaB proteins associated with cancer and inflammation

Oncology - Nerve growth factor modulates cellular interactions in primary liver cancer

Oncology - New hypothesis on how high disease burden may explain low cancer burden

Oncology - Survivin may be suited for tumor-specific gene promotion in melanoma

Oncolysis - Microarray explores adenovirus-mediated E2F-1-induced apoptosis

Osteoarthritis - Cartilage degeneration of human joints varies

Ovarian Cancer - Researchers evaluating investigational therapy for ovarian cancer

Pancreatitis - Specific T cells can induce pancreatitis in rats that is similar to human AIP

Parkinson Disease - Dopaminergic neurons from monkey ESCs function in Parkinson primate model

Patents - Biotech company's ProCord granted European patent

Pediatric Cancer Therapy - Rasburicase effective for treatment of cancer-related hyperuricemia

Pediatric Oncology - Adenovirus hepatitis is fatal to children who receive chemotherapy for leukemia

Pediatric Vaccines - Parental decisions about MMR vaccinations influenced by emotion

Personnel - Christopher Henney named board chair by immunology-focused biotechnology company

Personnel - Keith Yamamoto, PhD, appointed to chair of scientific advisory board

Personnel - Madhusudan V. Peshwa, PhD, named VP, R&D by clinical stage therapeutics company

Philanthropy - Grants support public awareness initiatives for global disease prevention

Phosphatase - Glucosidase inhibitor antiviral nature, role of alkaline phosphatase shown

Plague -  Yersinia pestis outbreak strains susceptible to antimicrobials

Pneumococcal Vaccines - Data advance knowledge in pneumococcal vaccines research

Pneumocystis Infection -  Pneumocystis outbreak transmitted within pediatric transplant unit

Pneumocystis Infection - General population may be a reservoir of Pneumocystis jirovecii

Polio Vaccine - Antibody against poliovirus blocks poliovirus-induced cytopathic effect

Product Licensing - Anti IL-5 receptor antibody licensed from Kyowa Hakko Kogyo Co., Ltd.

Proteomics - Findings in proteomics provide new insights

Proteomics - Neutrophils use a paracrine feedforward mechanism to promote angiogenesis

Respiratory Medicine - British team discovers new weapon for asthmatics

Respiratory Medicine - Corrected lymphangiogenesis ameliorates airway inflammation and asthma

Respiratory Syncytial Virus - DNA vaccine effective against respiratory syncytial virus in calves

Rotavirus Vaccine - Non-human primate model of rotavirus infection developed

Rotavirus Vaccine - Precipitation of bovine rotavirus used to produce antibodies

SARS - Quarantine for SARS indirectly reduces infections

SARS Coronavirus - Researchers' findings advance SARS coronavirus research

SARS Outbreak - SARS needs to be distinguished from other febrile respiratory illnesses

SARS Prevention - Findings describe new data in SARS prevention research

SARS Vaccine - Antibodies binding to SARS spike and nucleocapsid proteins identified

SARS Vaccine - Fragment 450-650 of SARS coronavirus spike protein purified

SARS Vaccines - New findings in the area of SARS vaccines detailed

SARS Virus - Evasion of antibody neutralization in SARS coronaviruses investigated

Schistosomiasis Vaccine - Immune response to schistosomiasis DNA vaccine in baboon described

Sciatic Nerve - Cuff electrode implantation linked to upregulation of TNF-alpha and TGF-beta1

Smallpox - Surveillance and control measures during smallpox outbreaks reviewed

Smallpox Vaccine - Role of smallpox vaccination in biowarfare prevention discussed

Smallpox Vaccines - Researchers provide details of new studies and findings in the area of smallpox vaccines

Soft Tissue Cancer - Case of sarcomatoid carcinoma of renal pelvis with giant cell tumors reported

Stem Cell Research - ESC-derived atrial cardiomyocytes identified during early development

Stem Cell Research - Exposure to young systemic environment rejuvenates aged progenitor cells

Stem Cell Research - Genistein stimulates osteoblastic differentiation via NO/cGMP in bone marrow

Stem Cell Research - Germline stem cells resemble undifferentiated spermatogonia in adult testis

Stem Cell Research - Hematopoietic stem cells identified from dermal papillae of hair follicles

Stem Cell Research - High-field MRI allows tracking of minimal number of cells

Stem Cell Research - Human reaming debris is a source of multipotent stem cells

Stem Cell Research - Laminin-5 induces osteogenic gene expression in MSCs via ERK-dependent pathway

Stem Cell Research - Mechanisms controlling primordial germ cell proliferation in females explored

Stem Cell Research - Oct-4 may be crucial in SC property of spermatogonia but not in cell survival

Stem Cell Research - SCL enhancer directs oncogenic fusion genes into stem cells

Stem Cell Research - SP cells share transcriptome signatures/express tissue-specific markers

Stem Cell Research - T cells differentiated with anti-CD3/anti-CD28 in presence of TGF-beta

Stem Cell Transplantation - HLA antigens risk/protective factors for acute GVHD in HLA-identical SCT

Stem Cell Transplantation - RT-PCR enables pre-emptive management of EBV reactivation after ASCT

Stem Cell Transplantation - cDNA library identifies HLA class II-restricted peptides recognized by CD4 cells

Streptococcus Vaccine - FAI protein of streptococci targets B cells and has adjuvant activity

Systemic Lupus Erythematosus - Antibody-induced IL-2 deficiency could cause autoantibody production in lupus

Tick-Borne Disease - Serine protease inhibitor shows promise as anti-tick vaccine

Tissue Engineering - Bone repair with form of BMP-2 incorporates into fibrin cell ingrowth matrices

Tissue Engineering - Ceramic implants induce more bone formation than titanium implants

Tissue Engineering - Human platelet supernatant can lead to chondrocyte dedifferentiation

Tissue Engineering - Hyaluronic acid used to coat surfaces through direct immobilization

Tissue Engineering - Keratinocyte culture system developed for use in skin wound closure

Tissue Engineering - Modified biodegradable scaffolds used for cartilage tissue engineering

Tissue Engineering - PLG microspheres are a moldable scaffold for cartilage tissue engineering

Tissue Engineering - Peptide-immobilized nanoporous alumina membranes enhance osteoblast adhesion

Tissue Engineering - Self-gelling hydrogels are based on oppositely charged dextran microspheres

Tissue Engineering - Tissue engineering schemes developed by artificial intelligence

Tissue Engineering - Vascular patches tissue-engineered with bone marrow-derived cells

Tobacco Use - CYP2S1 not involved in activation of cigarette smoke carcinogens

Tobacco Use - Increased levels of metallothionein found in placenta of smokers

Transplant Medicine - FK778 prolongs cardiac allograft survival

Transplant Medicine - Liver donor-specific IFN-gamma-producing cells denote HCV recurrence risk

Tuberculosis - Fixed dose combinations for TB helps prevent emergence of drug resistance

Tuberculosis - Pathogen-induced microenvironments exist within host cell endosomal system

Tuberculosis - Proportion method for drug resistant-TB determination not supported by research

Tuberculosis - Pyrosequencing differentiates between M. tuberculosis complex species

Tuberculosis - TB group, GlaxoSmithKline announce joint drug discovery program for TV therapies

Tuberculosis Control - Tuberculosis control programs in China may exclude poor people

Tuberculosis Diagnostics - Heat-fixed unstained sputum AFB smears stable up to 10 months

Tuberculosis Therapy - Diamine-based antituberculosis drug inhibits intracellular M. tuberculosis

Tuberculosis Therapy - Majority of MDR-TB isolates in Thailand susceptible to second-line drugs

Tuberculosis Treatment - Melatonin prevents free radical/MADD metabolic profiles induced by anti-TB drugs

Tuberculosis Vaccine -  M. tuberculosis protein epitopes with vaccine potential identified

Tuberculosis Vaccine - BCG vaccine protects girls against lower respiratory tract infections

Tuberculosis Vaccine - Factors influencing immune response to BCG vaccine antigens outlined

Tuberculosis Vaccines - Research add new data to tuberculosis vaccines body of knowledge

Type 1 Diabetes Research - Scientists at diabetes center find genetic defects in immunological tolerance

Urology - Findings describe new data in urology research

Vaccine Adjuvant - Effect of ovalbumin phosphorylation on adjuvant adsorption reported

Vaccine Adjuvant - Local reaction from aluminum-containing vaccines in monkeys reported

Vaccine Delivery - Microencapsulation by solvent extraction/evaporation reviewed

Vaccine Development - Culture system developed for production of IgG2a monoclonal antibodies

Vaccine Development - Microemulsion systems for oral delivery of proteins characterized

Vaccine Development - Vaccine research and development is global science policy priority

Vaccine Efficacy - Difficulty in ranking states' immunization coverage outlined

Vaccine Safety - Automated method for quantifying polysorbate developed

Vaccine Vector - Efficiency of retroviral vectors controlled by plasmid to vector ratio

Vaccine Vector - Production of recombinant adeno-associated viral vectors described

Vaccine Vector - Virosome-mediated delivery of protein antigens in vivo described

Varicella Vaccine - Gelatin-free varicella vaccine is safe and immunogenic

Vector Development - Pyridinium cationic lipids are well-suited for non-viral gene delivery

Virology - Caffeine keeps retroviruses from transducing nondividing cells

Virology - Novel flavivirus or new lineage of West Nile Virus identified

Virology - Studies advance knowledge in virology research

Virology - Vaccinia virus penetration requires cholesterol

West Nile Virus - Moroccan West Nile virus isolates related to equine outbreaks in Mediterranean

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