Immunotherapy Weekly

Immunology - Leucocytapheresis renews interferon efficacy in hepatitis C-infected patients

Immunology - Nutrition gene key in regulating immune system

Immunology - Studies advance knowledge in immunology research

Infectious Disease - Results presented on investigational West Nile virus vaccine

Infectious Disease - Weakened T-cell receptor signals change T-cell lineage

Infectious Disease Research - NIAID-supported research combats/elucidates emerging infectious diseases

Influenza Vaccine -  Bacillus firmus enhances immune response to influenza virus

Influenza Vaccine - Influenza vaccination safe in second or third trimester of pregnancy

Influenza Vaccine - Neuraminidase-lacking influenza mutant protects against infection

Kaposi Sarcoma-Associated Herpesvirus - Recent findings in kaposi sarcoma-associated herpesvirus described

Kidney Cancer - Cytokine gene polymorphisms linked to potential risk and protective factors

Leukemia - Survival of a child with ALL and Scedosporium prolificans infection examined

Lichen Sclerosus - Immune dysregulation in lichen sclerosus observed

Liver Cancer - Researchers' findings advance liver cancer research

Liver Cancer Vaccine - scFv with tumoricidal activity against liver cancer constructed

Lung Cancer -  M. tuberculosis infection associated with FHIT gene LOH in lung cancer

Lung Cancer - C-C chemokine receptor 5 on stromal cells promotes pulmonary metastasis

Lung Transplantation - Female lung transplant recipients at greater risk of acute lung injury

Lymphoma - CXCR3-positive B cells attracted by MIG might belong to the lymphoma clone

Lymphoma - Novel chemical classes identified as potential Pim1 inhibitors

Malaria - Studies describe new findings in malaria research

Malaria Vaccines - Findings describe new data in malaria vaccines research

Matrix Molecules - Alveolar bone matrix molecules studied, characterized immunohistochemically

Measles Virus - Measles virus infection analyzed, HLA-DRB1-bound self-peptides identified

Melanoma - Boosting immunity, cutting off tumor oxygen supply, may improve survival

Melanoma - Results from phase II MEL 1 immunotherapy study results reported

Melanoma Vaccines - New findings in the area of melanoma vaccines described

Meningitis - Distinct lineage of echovirus 30 probable cause of aseptic meningitis outbreak

Meningococcal Vaccine -  Neisseria outer-membrane proteins rapidly characterized

Menstrual Cycle - Asthma and hay fever linked to irregular periods

Merkel Cell Cancer - Diagnosis and management strategies for Merkel cell carcinoma of skin described

Metastatic Melanoma - Pharmaceutical company presents design of phase 3 melanoma trial at ASCO

Methicillin-Resistant Staphylococcus Aureus - Soap-sharing/pre-existing cuts caused recurring MRSA infections in football team

Mosquito-Borne Disease - Shifting epidemiology of flaviviridae reported

Multiple Sclerosis - FOCIS 2005 presentation: XIAP, a novel target in multiple sclerosis

Multiple Sclerosis - Recent findings illuminate research in multiple sclerosis

Mumps Vaccine - Epidemiology of mumps in Poland from 1990 to 2003 reviewed

Mycobacterium Smegmatis -  M. smegmatis mutants unable to grow at low pH in the presence of CCCP

Mycobacterium Smegmatis -  M. smegmatis re1A homolog affects cell appearance/viability/gene expression

Mycobacterium Tuberculosis - MTB mycolic acid elicits pathogen-associated host innate immune responses

Mycobacterium Vaccine - Mycobacteria heat shock protein interacts with antigen-presenting cells

Neisseria - Complement protein deficiency promotes Neisseria infections

Neural Stem Cell Research - Glial-derived nexin transforms HEK cells into neuron-like cells

Neural Stem Cell Research - Nandrolone influences neural stem cell proliferation and neurogenesis

Neural Stem Cell Research - P21 loss compromises adult neural stem cell relative quiescence

Neural Stem Cell Research - Simultaneous Olig2/Nkx2.2 cDNA transfection differentiates oligodendrocytes

Neurogenesis - D3 dopamine receptors do not regulate neurogenesis in subventricular zone

Neuroscience - Researchers' findings advance neuroscience research

Non-Hodgkin Lymphoma - Researchers find way to streamline new lymphoma treatment

Non-Small Cell Lung Cancer - Data from phase I/II study of GemVax peptide vaccine GV1001 presented

Norovirus - Factors identified with bovine norovirus seropositivity in veterinarians

Norovirus Outbreaks - GII/5 was dominant genotype in norovirus outbreak in Japan

Nosocomial Infections - National medical agency grants special compassionate use for diarrhea therapy

Nuclear Magnetic Resonance - F-19 NMR is a versatile reporter for non-invasive physiology and pharmacology

Nucleopolyhedrovirus - Nucleopolyhedrovirus epizootics initiate decline of N. abietis populations

Obesity Epidemic - Obesity epidemic is harbinger of metabolic disorder epidemic

Obstetrics - Etiology of nonimmune fetal hydrops studied in southern Thailand

Oncology - Thalidomide enlists a multifaceted approach to treating multiple myeloma

Otitis Media - Overcoming obstacles to vaccines for otitis media discussed

Ovarian Cancer - Lymph node sampling prognosticated early stage epithelial ovarian carcinoma

Pain Management - COX-2 inhibitors may be used with care in older patients

Pancreatic Cancer - Update on dose-escalation trial of pancreatic cancer therapy 'encouraging'

Pancreatic Cancer Vaccine - Personalized peptide vaccine shows promise for pancreatic cancer

Pediatric Vaccine - Study of immunization status in public care system conducted

Pediatrics - Interleukins foster hepatitis B clearance in chronically infected children

Peripheral Blood - Peripheral blood basophils studied, differential kinase role in signaling shown

Personnel - Chronic rhinosinusitis therapeutics company elects board member

Philanthropy - Center for Molecular Biotechnology gets grant for trypanosomiasis research

Phosphorylation - RhoE function examined, regulation by ROCK I-mediated phosphorylation shown

Photoreceptors - Ciliary neurotrophic factor receptor studied, immunolocalization reported

Pneumococcal Pneumonia - CD11b inhibits S. pneumoniae outgrowth and dissemination in mice

Polio - Managing human resources for polio eradication program described

Prions - Peyer's patches interfaces analyzed, neuroinvasion in prion diseases indicated

Prostate Cancer - Clinical data on targeted prostate cancer therapy presented at ocology meeting

Prostate Cancer - HLA-DRB1*1501-restricted T-cell epitopes from PSA identified

Prostate Cancer Vaccine - Updated positive phase 2 data of prostate cancer vaccine presented at meeting

Protein Kinase C - Amphetamine-stimulated dopamine efflux studied, regulation clarified

Proteomics - Recent findings illuminate research in proteomics

Psoriatic Arthritis - Basal autoantibody levels in biological agent-naive patients determined

Psoriatic Arthritis - FDA approves REMICADE for ninth indication: psoriatic arthritis

Pulmonary Medicine - Bronchoalveolar lavage studied, cytokine profile and proteome analysis reported

Pulmonary Medicine - Interleukin-1 beta examined, effects in adult murine lung defined

Rabies - Stochastic special model predicts spatial dynamics for raccoon rabies emergence

Renal Failure - Sirolimus may regress Kaposi sarcoma in renal graft recipients

Respiratory Syncytial Virus - Research add new data to respiratory syncytial virus body of knowledge

Retroviruses - TRIM5 alpha proteins block retrovirus infections across primate species

SARS Coronavirus - Anti-SARS-coronavirus activity of cepharanthine determined

SARS Vaccine - Spike glycoprotein polypeptide protects against SARS infection

Sexual & Reproductive Health - Cervical cancer vaccine produces high anti-HPV immune response in adolescents

Signaling Pathways - NF-kappa B examined, peptide-mediated interference of activation revealed

Simian Immunodeficiency Virus - Active SIV CNS infection correlates with neurological disease

Smallpox Vaccine - Experiences of smallpox vaccination clinic reported

Smallpox Vaccines - Research in smallpox vaccines provides new insights

Spinal Cord Regeneration - Corticospinal regeneration into lumbar gray matter reason for locomotor recovery

Stem Cell Research - Activated CB DCs kill tumor cells without damaging normal hematological SCs

Stem Cell Research - Basic FGF supports undifferentiated ESC growth without conditioned medium

Stem Cell Research - Intervertebral disc-like cells induced from adult mesenchymal stem cells

Stem Cell Research - Nestin-positive mesenchymal SCs differentiate into excitable neuron-like cells

Stem Cell Research - Notch has role in regulating exocrine progenitor pool

Stem Cell Research - Pit-1 induces hepatic SC differentiation into prolactin-producing cells

Stem Cell Research - Scientists join to develop laboratory model of immune system

Stem Cell Research - Three type of ionic currents identified in mesenchymal stem cells from BM

Stem Cell Research - Transplanted B-stem cells reconstitute bone marrow B-cells after irradiation

Stem Cell Research - Valproic acid stimulates proliferation/self-renewal of hematopoietic stem cells

Stem Cell Transplantation - Embryonic stem cells may be future therapy for inner ear diseases

Stem Cell Transplantation - Fc gamma RIIa-polymorphic site potential target for acute GVHD in allogeneic SCT

Stem Cell Transplantation - Higher CD34 cell dose can reduce pulmonary mortality after TBI-based regimens

Stem Cell Transplantation - New data illuminates research in stem cell transplantation

Stem Cell Transplantation - Race associated with survival after ASCT from IIIA-matched unrelated donors

Stem Cell Transplantation - Thymic recovery onset/thymic output plateau differentially regulated after SCT

Streptococcus Vaccine - Mucosal vaccine of Streptococcus antigens enhances bacterial clearance

Streptococcus Vaccines - Reports add new data to streptococcus vaccines research

Thyroid Cancer - AEE788 covers dual targets in anaplastic thyroid carcinoma

Tissue Engineering - 3D femtosecond laser patterning of collagen used for directed cell attachment

Tissue Engineering - Bioactive glasses able to modulate macrophages and monocytes

Tissue Engineering - Chitin-based tubes used for tissue engineering in nervous system

Tissue Engineering - Endothelial cells proliferate on adhesive protein-free synthetic polymer gels

Tissue Engineering - Endothelium directly cocultured on smooth muscle cells

Tissue Engineering - MSCs engineered for total ankle joint repairs for osteoarthritis

Tissue Engineering - Minimal porous PPF scaffold degradation occurs following implantation

Tissue Engineering - Nanoporous alumina membranes improve osteoblast adhesion and proliferation

Tissue Engineering - Reports advance knowledge in tissue engineering research

Toxoplasmosis Vaccine -  Salmonella typhimurium vaccine protects against Toxoplasma gondii

Transplant Medicine - Arkansas university medical team performs first liver transplant in state

Transplant Medicine - Early corticosteroid cessation studied in renal transplant recipients

Transplant Medicine - HLA-A, DGF increases risk for rejection in kidney-pancreas transplant recipients

Transplant Medicine - Hepatitis C virus core protein potentiates cyclosporine immunosuppression

Transplant Medicine - High-immunologic-risk patients may be able to undergo early steroid withdrawal

Transplant Medicine - Sirolimus added to cyclosporine helps with steroid withdrawal

Transplant Medicine - Synthetic myriocin analogue FTY720 deters tumor growth and angiogenesis

Transplant Medicine - T-cell costimulatory molecule promotes long-term survival in skin allografts

Transplantation Medicine - Cross-MHC functional tolerance toward face grafts examined in mice

Transplantation Medicine - New crossmatch technique eliminates antibody interference

Tuberculosis - Ipr1 gene mediates innate immunity to tuberculosis

Tuberculosis - Multiple factors influence inability to control tuberculosis in China

Tuberculosis - PI3P retention different in phagosomes containing live or dead mycobacteria

Tuberculosis - Tuberculosis decline in Netherlands over the past decade result of cohort effect

Tuberculosis - Two cases of lupus vulgaris reported

Tuberculosis Drug Development - Quinoxaline-2-carboxylate 1,4-dioxide derivatives have anti-MTB activity

Tuberculosis Vaccine - Utility of tuberculin skin tests in Middle East reported

Typhus Vaccine -  Orientia tsutsugamushi antigen protects against scrub typhus

Umbilical Cord Blood Banking - Umbilical cord blood banking promises families biological "insurance"

Umbilical Cord Blood Transplantation - Modified cord blood collection method achieves sufficient cell levels for CBT

Vaccine Adjuvant - Homotopes affect primary and secondary antibody responses in poultry

Vaccine Development - Biopharma company begins studies of vaccine to produce antistaph antibodies

Vaccine Development - Immunologic uniqueness of genital tract poses vaccine challenges

Vaccine Development - Mucosal adjuvants and vaccines based on cholera toxin and CpG reviewed

Vaccine Development - Past, present and future vaccines reviewed

Vaccine Development - Proteomic profiling of E. coli fermentation improved protein production

Vaccine Efficacy - Macrophage function defect reduces response to polysaccharide antigens

Vaccine Policy - Policymakers' views of new vaccine introduction in Asia reported

Vaccine Vector - Fractal structure of polycation-DNA complexes reported

Vaccine Vector - Immune response to transgenes delivered by adenoviral vectors examined

Vaccine Vector - Lentiviral vectors target hematopoietic cells

Vaccine Vector - Oncolytic HSV vector delivered to metastatic breast cancer in brain

Vector Development - Researchers provide details of new studies and findings in the area of vector development

Virology Vaccine - Vaccinia virus protein contributes to virulence

Virology Vaccine - Vaccinia virus protein essential complex component for virus entry

Warts - Dermatologists use immunotherapy to treat warts

Wegeners Granulomatosis - Researchers note factors leading to accelerated atherosclerosis in WG patients

Wound Care - U.S. FDA grants clearance for absorbant antimicrobial barrier dressing

Yersinia Pestis -  Y. pestis CRISPR elements acquire new repeats by bacteriophage DNA uptake