Hypoxia

Hypoxia analyzed, effect of lipopolysaccharide-induced lung injury defined

Published in Immunotherapy Weekly, August 31st, 2005

According to recently published research from Switzerland, hypoxia aggravates lipopolysaccharide-induced lung injury.

"The animal model of inflammatory response induced by intratracheal application of lipopolysaccharide includes many typical features of acute lung injury or the acute respiratory distress syndrome. A number of experimental investigations have been performed to characterize the nature of this injury more effectively," wrote D. Vuichard and colleagues, University of Zurich.

"In inflammatory conditions, hypoxia occurs frequently before and in parallel with pulmonary and non-pulmonary pathological events. This current study was designed...

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Source: Immunotherapy Weekly (2005-08-31)

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