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Rheumatoid Arthritis

Pyrimethamine effective second-line treatment against rheumatoid arthritis

Published in Immunotherapy Weekly, November 2nd, 2005

Scientists in Iran report pyrimethamine is effective against arthritis.

"Recent evidence has shown that the antimalarials are useful drugs in the treatment of various rheumatic diseases. The present study was designed to test the therapeutic effect of pyrimethamine (PYR) in collagen-induced arthritis (CIA)," explained F. Saadat and associates at Tehran University of Medical Science in a recent issue of the journal Medical Science Monitor.

The researchers reported, "CIA was induced in Lewis rats. The intraperitoneal administration of PYR and methotrexate (MTX) were started on day 25 post-immunization and continued until final assessment on day...

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