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HIV/AIDS Therapy

Topical microbicide prevents and/or treats oculo-genital adenovirus/HIV infections

Published in Immunotherapy Weekly, January 4th, 2006

The topical microbicide stampidine prevents and/or treats oculo-genital adenovirus/HIV infections.

"Adenoviruses (ADVs) are causative agents of severe and extremely contagious ocular and genital infections associated with conjunctivitis, genital ulcers and urethritis. Yet no functional antiviral compounds are currently available against adenoviral infections," investigators in the United States report.

According to O.J. Dcruz and colleagues at Parker Hughes Institute in St. Paul, "We discovered halogen-substituted phenyl phosphoramidate derivatives of stavudine (STV/d4T) as a new class of dual-function anti-human immunodeficiency virus (HIV) agents...

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