Published in Immunotherapy Weekly, January 4th, 2006
"There is increasing in vitro evidence to support a role for VEGF, a major regulator of angiogenesis, as a mediator of fibrosis associated with neovascularization. We tested the hypothesis that VEGF is involved both in increased airway mucosal vascularity and in the subepithelial fibrosis of asthmatic patients," researchers in Italy report.
"Bronchial biopsies were performed in 24 asthmatic patients and eight healthy controls. Immunostaining, using computerized image analysis, was performed using monoclonal antibodies against VEGF+ cells, type...
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