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Immunotherapy Weekly

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Allergy & Immunology



Cytomegalovirus infection inhibits immune responses generated against P. carinii



February 8th, 2006

Cytomegalovirus infection inhibits immune responses generated against Pneumocystis carinii.

According to recent research from the United States, "Despite the use of antimicrobial prophylaxis, cytomegalovirus (CMV) and Pneumocystis carinii (PC) pneumonia (PCP) are both leading causes of morbidity and mortality in immunocompromised patients."

"It has previously been reported that CMV infection modulates host immune responses with a variety of mechanisms which include the suppression of helper T cell functions and antigen presenting cell (APC) functions, both of which are critical for PCP resolution.

"However," M.H....


Source: Immunotherapy Weekly (2006-02-08)

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