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Allergy & Immunology
PKR plays critical role in immune response regulation to mycobacterial infection
February 8th, 2006
PKR plays a critical role in immune response regulation to mycobacterial infection. According to recent research from People's Republic of China, "Following infection of the host by Mycobacterium tuberculosis, induction of cytokines is a major defense mechanism to limit the pathogen invasion. Cytokines interact with each other to form an intertwined network of pathways. "For example, IFN and TNF have been shown to interact through common pathways including IFN-inducible, dsRNA-activated serine/threonine protein kinase (PKR) induction." "As a signal transducer," said B.K. Cheung and colleagues at the University of Hong Kong,...
Source: Immunotherapy Weekly (2006-02-08)
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