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Immunotherapy Weekly

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Anthrax Vaccine



Anthrax spore vaccines based on toxin components have been developed



February 8th, 2006

Researchers have developed efficacious, nontoxigenic Bacillus anthracis spore vaccines based on strains expressing mutant variants of lethal toxin components.

According to recent research published in the journal Vaccine, "We reported previously on the development of a Bacillus anthracis vaccine strain expressing high levels of recombinant protective antigen (rPA). To further explore the potential of the B. anthracis platform, we generated several attenuated strains expressing lethal toxin components PA and LF, which are biologically inactive, yet retain their antigenic properties."

"A single injection of 5 x...


Source: Immunotherapy Weekly (2006-02-08)

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