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Asthma
Growth factor interactions may compel remodeling in the asthmatic airway
February 8th, 2006
Growth factor interactions may compel remodeling in the asthmatic airway. "Airway remodeling describes the structural changes that occur in the asthmatic airway that include airway smooth muscle hyperplasia, increases in vascularity due to angiogenesis, and thickening of the basement membrane. Our aim in this study was to examine the effect of transforming growth factor-beta on the release of connective tissue growth factor and vascular endothelial growth factor from human airway smooth muscle cells derived from asthmatic and nonasthmatic patients," researchers in Australia report. "In addition we studied the immunohistochemical localization of these...
Source: Immunotherapy Weekly (2006-02-08)
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