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Atherosclerosis Vaccine
Apo B-100-related epitope reduces atherosclerosis and plaque inflammation
February 8th, 2006
Immunization using an Apo B-100-related epitope reduces atherosclerosis and plaque inflammation in hypercholesterolemic apo E-/- mice. According to scientists in the United States and Sweden, "Immune system modulates atherosclerosis and immunization using homologous LDL reduces atherosclerosis in hyperlipidemic animals. The nature of athero-protective antigenic epitopes in LDL remains unclear." "We have recently identified nearly a 100 antigenic epitopes in human apo B-100 and in this study we evaluated the effects of immunization with two such epitopes on atherosclerosis in hypercholesterolemic apo E -/- mice. Male apo E...
Source: Immunotherapy Weekly (2006-02-08)
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