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Immunotherapy Weekly

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Bacteriology



Toll-like receptors are sentinels of host defense against bacteria



February 8th, 2006

Toll-like receptors are sentinels of host defense against bacterial infections.

According to a report from Germany and Canada, "Innate immunity provides a first line of host defense against infection through microbial recognition and killing while simultaneously activating a definitive adaptive immune response. Toll-like receptors (TLRs) are principal mediators of rapid microbial recognition and function mainly by detection of structural patterns that do not exist in the host."

Markus Schnare and collaborators at the University of Erlangen-Nuremberg in Germany and McGill University in Canada wrote, "TLR2 and TLR4 were the first members of this innate...


Source: Immunotherapy Weekly (2006-02-08)

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