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Immunotherapy Weekly

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Breast Cancer Vaccine



Livin may be a major breast cancer antigen



February 8th, 2006

Livin may be a major breast cancer antigen.

According to a study from Japan, "Survivin and livin are highly expressed in cancer cells and transformed cells, but show little or no expression in normal differentiated tissues. Human antibody responses to tumor-associated antigens have been detected, but little is known about the response to survivin and livin in breast cancer patients. We examined the prevalence of anti-survivin and livin antibodies in breast cancer patients with a specific enzyme-linked immunosorbent assay (ELISA) using recombinant protein."

"Using a cutoff value for positivity determined as the mean absorbance +2SD for healthy control...


Source: Immunotherapy Weekly (2006-02-08)

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