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Chlamydia Vaccine
Vaccination of newborn mice protects against Chlamydia trachomatis
February 8th, 2006
Vaccination of newborn mice induces a strong protective immune response against respiratory and genital challenges with Chlamydia trachomatis. "Chlamydia trachomatis infections can occur early in life and may result in long-term sequelae. To assess the feasibility of implementing a vaccine in newborns, groups of two-day-old BALB/c mice were immunized intranasally (i.n.) with 1 x 104 inclusion forming units (IFU) of C. trachomatis mouse pneumonitis (MoPn). As a control, newborn mice were sham-immunized i.n. with minimal essential medium. In the vaccinated animals, strong Chlamydia-specific humoral and cell-mediated immune responses...
Source: Immunotherapy Weekly (2006-02-08)
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