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Contraceptive Vaccine
Adverse reactions to Freund's-adjuvanted immunocontraceptives were found in domestic cats
February 8th, 2006
Investigators report adverse reactions to Freund's-adjuvanted porcine zona pellucida immunocontraceptives in domestic cats in a recent issue of Vaccine. According to researchers in the United States, "A vaccine of native PZP with Freund's adjuvant has been widely used in zoo and wild ungulates, but safety in felids has not been evaluated." "General health, immune response, and ovarian histology were assessed in five domestic cats vaccinated with PZP-Freund's and live cats given Freund's adjuvant alone," said Linda Munson at the University of California-Davis and collaborators in the U.S. "Peak antibody titers occurred three weeks after the...
Source: Immunotherapy Weekly (2006-02-08)
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