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Immunotherapy Weekly

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Cystic Fibrosis Therapy



Model for cystic fibrosis gene therapy has been developed



February 8th, 2006

Scientists have developed a model for cystic fibrosis gene therapy

According to recent research from Canada and the United States, "Gene therapy vectors are mostly studied in cultured cells, rodents, and sometimes in non-human primates, but it is useful to test them in human tissue prior to clinical trials. In this study, we investigated the possibility of using human sweat glands as a model for testing cystic fibrosis (CF) gene therapy vectors."

"Human sweat glands are relatively easy to obtain from skin biopsy, and can be tested for CFTR function," said H. Lee at the University of Toronto and collaborators in Canada and the U.S. "Using patients'...


Source: Immunotherapy Weekly (2006-02-08)

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