Drug Development

Atherogenic inflammation may be target for therapeutic development of mycophenolate mofetil

Published in Immunotherapy Weekly, April 5th, 2006

An overview of the potential anti-atherogenic properties of mycophenolate mofetil is presented in a recent issue of Cardiovascular Research.

According to the review from The Netherlands, "Atherosclerosis is characterized by a persistent, low-grade inflammatory state in which immune cell activation is inseparably linked to plaque formation and destabilization. The T-lymphocyte in particular has emerged as a pivotal player throughout the course of atherogenesis."

"As a consequence," explained S.I. van Leuven and colleagues at the Academic Medical Center in Meibergdreef, "the concept that immune modulation is a suitable target for cardiovascular...

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Source: Immunotherapy Weekly (2006-04-05)

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