Infectious Diseases
Severe sepsis exacerbates cell-mediated immunity in the lung
Published in Immunotherapy Weekly, August 9th, 2006
"Severe sepsis leads to long-term alterations in the immune response of surviving individuals. We have modeled this alteration in host immunity by studying the survivors of severe experimental sepsis (murine cecal ligation and puncture), which were subsequently challenged with lung granuloma-inducing Schistosoma mansoni eggs," wrote H.T. Wen and colleagues, University of Michigan.
"This granulomatous response is a well-studied cell-mediated immune reaction characterized by elevated...
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Source: Immunotherapy Weekly (2006-08-09)
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