Published in Immunotherapy Weekly, August 9th, 2006
Study 1: Both CD4+ and CD8+ T cells can mediate vaccine-induced protection against Coccidioides immitis infection in mice.
According to a study from the United States, "To determine which lymphocytes are required for vaccine-induced immunity to coccidioidomycosis, we used a temperature-sensitive mutant of Coccidioides immitis to immunize mice lacking subsets of lymphocytes or specific cytokines and infected the mice four weeks later with virulent C. immitis. After two weeks, we determined the number of fungi in their lungs and spleens. Vaccine-induced...
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