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Immunotherapy Weekly

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Asthma Immunology



Findings from University of Newcastle, Hunter Medical Research Institute provide new insights into asthma immunology



April 11th, 2007

New research, "Innate immune activation in neutrophilic asthma and bronchiectasis," is the subject of a report. According to recent research published in the journal Thorax, "The role of the innate immune system in the pathogenesis of asthma is unclear. Activation of innate immune receptors in response to bacterial lipopolysaccharide, viral infection and particulate matter triggers a pre-programmed inflammatory response, which involves interleukin (IL)8 and neutrophil influx."

"The inflammatory response in asthma is heterogeneous. To test the hypothesis that innate immune activation may be a relevant inflammatory mechanism in neutrophilic asthma where IL8 levels...


Source: Immunotherapy Weekly (2007-04-11)

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