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Malaria Vaccines
Studies conducted at National Institute for Medical Research, Medical Research Division on malaria vaccines recently published
April 11th, 2007
A report, "Fine mapping of an epitope recognized by an invasion-inhibitory monoclonal antibody on the malaria vaccine candidate apical membrane antigen 1," is newly published data in Journal of Biological Chemistry. "Antibodies that inhibit red blood cell invasion by the Plasmodium merozoite block the erythrocytic cycle responsible for clinical malaria. The invasion-inhibitory monoclonal antibody (mAb) 4G2 recognizes a conserved epitope in the ectodomain of the essential Plasmodium falciparum microneme protein and vaccine candidate, apical membrane antigen 1 (PfAMA1)," scientists writing in the Journal of Biological Chemistry report. "Here we...
Source: Immunotherapy Weekly (2007-04-11)
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