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Immunotherapy Weekly

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Monoclonal Antibodies



New monoclonal antibodies study findings have been published by scientists at University of Tokyo



April 11th, 2007

Researchers detail in "Properties of blocking and non-blocking monoclonal antibodies specific for human macrophage galactose-type C-type lectin (MGL/ClecSF10A/CD301)," new data in monoclonal antibodies. According to recent research published in the Journal of Biochemistry, "Monoclonal antibodies (mAbs) specific for the human macrophage galactose-type calcium-type lectin (MGL) were established. The recombinant extracellular domain of MGL was used to immunize a mouse, and 10 hybridoma clones were obtained."

"Binding of recombinant MGL to asialo-bovine submaxillary mucin was shown to be blocked by mAbs MLD-1, 4 and 6. Immunoprecipitation of MGL from lysates of COS-1...


Source: Immunotherapy Weekly (2007-04-11)

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