Immunotherapy Weekly
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Monoclonal Antibodies
Recent findings in monoclonal antibodies described by researchers from National Institutes of Health
April 11th, 2007
New investigation results, "Anti-Tac (daclizumab, Zenapax) in the treatment of leukemia, autoimmune diseases, and in the prevention of allograft rejection: a 25-year personal odyssey," are detailed in a study published in Journal of Clinical Immunology. "Twenty-five years ago, we reported the production of the monoclonal antibody, anti-Tac that identifies the IL-2 receptor alpha subunit and blocks the interaction of IL-2 with this growth factor receptor. In 1997, daclizumab (Zenapax), the humanized form of this antibody, was approved by the FDA for use in the prevention of renal allograft rejection," scientists in the United States report. "In addition, we...
Source: Immunotherapy Weekly (2007-04-11)
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