Monoclonal Antibodies
Investigators at University of Louisville, Department of Medicine zero in on monoclonal antibodies
Published in Immunotherapy Weekly, August 29th, 2007
Data detailed in "Combined yeast {beta}-glucan and antitumor monoclonal antibody therapy requires C5a-mediated neutrophil chemotaxis via regulation of decay-accelerating factor CD55" have been presented. "Administration of a combination of yeast-derived beta-glucan with antitumor monoclonal antibodies (mAb) has significant therapeutic efficacy in a variety of syngeneic murine tumor models. We have now tested this strategy using human carcinomas implanted in immunocompromised severe combined immunodeficient mice," researchers in the United States report.
"Combined immunotherapy was therapeutically effective in vivo against NCI-H23 human non-small-cell lung carcinomas,...
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Source: Immunotherapy Weekly (2007-08-29)
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